Today we present 20 new placebo and nocebo research papers, comments and abstracts identified during September 2020. As usual, they are based on new PUBMED publication using the search terms „placebo“ and „nocebo“ and are hand-selected from more than 826 new publications during the preceding month. Previously published monthly updates can be found in our archive. Todays selection as well as all previously identified papers will also go into our placebo research library that currently contains more than 4,500 relevant papers. If you would like to get access to the full database, please register for our newsletter and provide us with your email address and affiliation.
Ambikaibalan, D., Quaade, A. S., Halling, A. S., Thyssen, J. P., & Egeberg, A. (2020).
Placebo Response in Phase 3 Trials of Systemic Therapies for Moderate-to-Severe Plaque Psoriasis: A Systematic Review and Meta-Analysis. Dermatology, 1-8. doi:10.1159/000509295
https://www.ncbi.nlm.nih.gov/pubmed/32894834
D’Amico, F., Solitano, V., Peyrin-Biroulet, L., & Danese, S. (2020).
Nocebo effect and biosimilars in inflammatory bowel diseases: what’s new and what’s next? Expert Opin Biol Ther, 1-9. doi:10.1080/14712598.2020.1817374
https://www.ncbi.nlm.nih.gov/pubmed/32857634
Evans, K., Romero, H., Spierings, E. L., & Katz, N. (2020).
The relation between the placebo response, observed treatment effect, and failure to meet primary endpoint: A systematic review of clinical trials of preventative pharmacological migraine treatments. Cephalalgia, 333102420960020. doi:10.1177/0333102420960020
https://www.ncbi.nlm.nih.gov/pubmed/32960658
Frangos, E., Ceko, M., Wang, B., Richards, E. A., Gracely, J. L., Colloca, L., Schweinhardt, P., & Bushnell, M. C. (2020).
Neural effects of placebo analgesia in fibromyalgia patients and healthy individuals. Pain. doi:10.1097/j.pain.0000000000002064
https://www.ncbi.nlm.nih.gov/pubmed/32925593
Frisaldi, E., Shaibani, A., & Benedetti, F. (2020).
Understanding the mechanisms of placebo and nocebo effects. Swiss Med Wkly, 150, w20340. doi:10.4414/smw.2020.20340
https://www.ncbi.nlm.nih.gov/pubmed/32920787
Hartmann, H., Rutgen, M., Riva, F., & Lamm, C. (2020).
Another’s pain in my brain: No evidence that placebo analgesia affects the sensory-discriminative component in empathy for pain. Neuroimage, 117397. doi:10.1016/j.neuroimage.2020.117397
https://www.ncbi.nlm.nih.gov/pubmed/32971262
Hofler, C., Osmani, F., & Schienle, A. (2020).
Placebo effects on the quantity and quality of relaxation training. J Health Psychol, 1359105320954238. doi:10.1177/1359105320954238
https://www.ncbi.nlm.nih.gov/pubmed/32873114
Holper, L., & Hengartner, M. P. (2020).
Comparative efficacy of placebos in short-term antidepressant trials for major depression: a secondary meta-analysis of placebo-controlled trials. BMC Psychiatry, 20(1), 437. doi:10.1186/s12888-020-02839-y
https://www.ncbi.nlm.nih.gov/pubmed/32894088
Howick, J., Webster, R. K., Rees, J. L., Turner, R., Macdonald, H., Price, A., Evers, A. W. M., Bishop, F., Collins, G. S., Bokelmann, K., Hopewell, S., Knottnerus, A., Lamb, S., Madigan, C., Napadow, V., Papanikitas, A. N., & Hoffmann, T. (2020).
TIDieR-Placebo: A guide and checklist for reporting placebo and sham controls. PLoS Med, 17(9), e1003294. doi:10.1371/journal.pmed.1003294
https://www.ncbi.nlm.nih.gov/pubmed/32956344
Hull, M. (2020).
Psychedelische Trips – auf Placebo! : Schlaganfallrisiko. MMW Fortschr Med, 162(16), 34. doi:10.1007/s15006-020-4377-9
https://www.ncbi.nlm.nih.gov/pubmed/32959291
Loder, E. W., & McGeeney, B. (2020).
Disentangling placebo effects in the treatment of migraine. Nat Rev Neurol. doi:10.1038/s41582-020-0406-7
https://www.ncbi.nlm.nih.gov/pubmed/32887960
Luu, S., Province, H., Berry-Kravis, E., Hagerman, R., Hessl, D., Vaidya, D., Lozano, R., Rosselot, H., Erickson, C., Kaufmann, W. E., & Budimirovic, D. B. (2020).
Response to Placebo in Fragile X Syndrome Clinical Trials: An Initial Analysis. Brain Sci, 10(9). doi:10.3390/brainsci10090629
https://www.ncbi.nlm.nih.gov/pubmed/32932789
Meissner, K., Lutter, D., von Toerne, C., Haile, A., Woods, S. C., Hoffmann, V., Ohmayer, U., Hauck, S. M., & Tschoep, M. H. (2020).
Molecular classification of the placebo effect in nausea. PLoS One, 15(9), e0238533. doi:10.1371/journal.pone.0238533
https://www.ncbi.nlm.nih.gov/pubmed/32966280
Momper, J. D., Green, D. J., Park, K., Burckart, G. J., & Snyder, D. L. (2020).
Ethical Considerations for Pediatric Placebo-Controlled Trials: FDA Outcomes and Perspectives. Ther Innov Regul Sci. doi:10.1007/s43441-020-00214-3
https://www.ncbi.nlm.nih.gov/pubmed/32901443
Nitzan, U., Carmeli, G., Chalamish, Y., Braw, Y., Kirsch, I., Shefet, D., Krieger, I., Mendlovic, S., Bloch, Y., & Lichtenberg, P. (2020).
Open-Label placebo for the treatment of unipolar depression: Results from a randomized controlled trial. J Affect Disord, 276, 707-710. doi:10.1016/j.jad.2020.07.077
https://www.ncbi.nlm.nih.gov/pubmed/32871704
Queiroz, N. S. F., Saad-Hossne, R., FrOes, R. S. B., Penna, F., Gabriel, S. B., Martins, A. L., & Teixeira, F. V. (2020).
Discontinuation Rates Following a Switch from a Reference to a Biosimilar Biologic in Patients with Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis. Arq Gastroenterol. doi:10.1590/S0004-2803.202000000-45
https://www.ncbi.nlm.nih.gov/pubmed/32935741
Solitano, V., D’Amico, F., Fiorino, G., Peyrin-Biroulet, L., & Danese, S. (2020).
Biosimilar switching in inflammatory bowel disease: from evidence to clinical practice. Expert Rev Clin Immunol, 1-10. doi:10.1080/1744666X.2021.1826311
https://www.ncbi.nlm.nih.gov/pubmed/32954893
Theodosis-Nobelos, P., Filotheidou, A., & Triantis, C. (2020).
The placebo phenomenon and the underlying mechanisms. Hormones (Athens). doi:10.1007/s42000-020-00243-5
https://www.ncbi.nlm.nih.gov/pubmed/32940864
Thomaidou, M. A., Veldhuijzen, D. S., Meulders, A., & Evers, A. W. M. (2020).
An experimental investigation into the mediating role of pain-related fear in boosting nocebo hyperalgesia. Pain. doi:10.1097/j.pain.0000000000002017
https://www.ncbi.nlm.nih.gov/pubmed/32910630
Vollert, J., Cook, N. R., Kaptchuk, T. J., Sehra, S. T., Tobias, D. K., & Hall, K. T. (2020).
Assessment of Placebo Response in Objective and Subjective Outcome Measures in Rheumatoid Arthritis Clinical Trials. JAMA Netw Open, 3(9), e2013196. doi:10.1001/jamanetworkopen.2020.13196
https://www.ncbi.nlm.nih.gov/pubmed/32936297