Today we present 25 new placebo and nocebo research papers, comments and abstracts identified during July 2021. As usual, they are based on new PUBMED publication using the search terms „placebo“ and „nocebo“ and are hand-selected from more than 823 new publications during the preceding month. Previously published monthly updates can be found in our archive. Todays selection as well as all previously identified papers will also go into our placebo research library that currently contains nearly 5,000 relevant papers. If you would like to get access to the full database, please register for our newsletter and provide us with your email address and affiliation.
An, S., Malani, V. D., & Setia, A. (2021).
The role of superstition in the placebo effect on memory performance. Cogn Process, 22(3), 553-558. doi:10.1007/s10339-021-01025-6
https://www.ncbi.nlm.nih.gov/pubmed/34231087
Bajcar, E. A., Wiercioch-Kuzianik, K., Farley, D., Buglewicz, E., Paulewicz, B., & Babel, P. (2021).
Order does matter: the combined effects of classical conditioning and verbal suggestions on placebo hypoalgesia and nocebo hyperalgesia. Pain, 162(8), 2237-2245. doi:10.1097/j.pain.0000000000002211
https://www.ncbi.nlm.nih.gov/pubmed/34256381
Bisconti, M., Venturin, D., Bianco, A., Capurso, V., & Giovannico, G. (2021).
Understanding Contextual Factors Effects and Their Implications for Italian Physiotherapists: Findings from a National Cross-Sectional Study. Healthcare, 9(6). doi:10.3390/healthcare9060689
https://www.ncbi.nlm.nih.gov/pubmed/34200302
Bliamptis, J., & Barnhill, A. (2021).
Physician perspectives on placebo ethics. J Med Ethics. doi:10.1136/medethics-2021-107446
https://www.ncbi.nlm.nih.gov/pubmed/34257086
Boorman, D. C., & Keay, K. A. (2021).
Escalating morphine dosage fails to elicit conditioned analgesia in a preclinical chronic neuropathic pain model. Behav Pharmacol. doi:10.1097/FBP.0000000000000642
https://www.ncbi.nlm.nih.gov/pubmed/34320522
Chvetzoff, R., Laurent, B., Baylot, D., & Chvetzoff, G. (2021).
[Scientific medicine and care relationship: From the therapeutic alliance to the therapeutic effect of the alliance]. Bull Cancer. doi:10.1016/j.bulcan.2021.02.011
https://www.ncbi.nlm.nih.gov/pubmed/34246457
De Vita, M. J., Maisto, S. A., Gilmour, C. E., McGuire, L., Tarvin, E., & Moskal, D. (2021).
The effects of cannabidiol and analgesic expectancies on experimental pain reactivity in healthy adults: A balanced placebo design trial. Exp Clin Psychopharmacol. doi:10.1037/pha0000465
https://www.ncbi.nlm.nih.gov/pubmed/34251840
Devlin, E. J., Whitford, H. S., Peoples, A. R., Morrow, G. R., Katragadda, S., Giguere, J. K., Naqvi, B. & Roscoe, J. (2021).
Psychological predictors of chemotherapy-induced nausea in women with breast cancer: Expectancies and perceived susceptibility. Eur J Cancer Care, e13488. doi:10.1111/ecc.13488
https://www.ncbi.nlm.nih.gov/pubmed/34323340
Eccles, R. (2021).
Placebo and Side Effects Confound Clinical Trials on New Antitussives. Lung. doi:10.1007/s00408-021-00458-2
https://www.ncbi.nlm.nih.gov/pubmed/34279718
Evans, K., Colloca, L., Pecina, M., & Katz, N. (2021).
What can be done to control the placebo response in clinical trials? A narrative review. Contemp Clin Trials, 107, 106503. doi:10.1016/j.cct.2021.106503
https://www.ncbi.nlm.nih.gov/pubmed/34237458
Frisaldi, E., Zamfira, D. A., & Benedetti, F. (2021).
The subthalamic nucleus and the placebo effect in Parkinson’s disease. Handb Clin Neurol, 180, 433-444. doi:10.1016/B978-0-12-820107-7.00027-6
https://www.ncbi.nlm.nih.gov/pubmed/34225946
Gras, A., Wardrope, A., Hirsch, E., Asadi Pooya, A. A., Duncan, R., Gigineishvili, D., Hingray, C., Kanemoto, K., Ladino, L., LaFrance, W. C., McGonigal, A., Pretorius, C., Valenti Hirsch, P., Vidailhet, P., Zhou, D. & Reuber, M. (2021).
Use of suggestive seizure manipulation methods in the investigation of patients with possible psychogenic nonepileptic seizures – An international ILAE survey. Epilepsia Open. doi:10.1002/epi4.12521
https://www.ncbi.nlm.nih.gov/pubmed/34288577
Hafliethadottir, S. H., Juhl, C. B., Nielsen, S. M., Henriksen, M., Harris, I. A., Bliddal, H., & Christensen, R. (2021).
Placebo response and effect in randomized clinical trials: meta-research with focus on contextual effects. Trials, 22(1), 493. doi:10.1186/s13063-021-05454-8
https://www.ncbi.nlm.nih.gov/pubmed/34311793
Hartmann, H., Riva, F., Rutgen, M., & Lamm, C. (2021).
Placebo Analgesia Does Not Reduce Empathy for Naturalistic Depictions of Others’ Pain in a Somatosensory Specific Way. Cereb Cortex Commun, 2(3), tgab039. doi:10.1093/texcom/tgab039
https://www.ncbi.nlm.nih.gov/pubmed/34296184
Hoenemeyer, T. W., Baidwan, N. K., Hall, K., Kaptchuk, T. J., Fontaine, K. R., & Mehta, T. S. (2021).
An Exploratory Analysis of the Association Between Catechol-O-Methyltransferase and Response to a Randomized Open-Label Placebo Treatment for Cancer-Related Fatigue. Front Psychiatry, 12, 684556. doi:10.3389/fpsyt.2021.684556
https://www.ncbi.nlm.nih.gov/pubmed/34267689
McCarter, G. (2020).
Harnessing Placebo Responses to Improve Health Outcomes. Am J Pharm Educ, 84(12), 8184. doi:10.5688/ajpe8184
https://www.ncbi.nlm.nih.gov/pubmed/34283778
Migliorini, F., Maffulli, N., Eschweiler, J., Betsch, M., Tingart, M., & Colarossi, G. (2021).
Placebo effect in pharmacological management of fibromyalgia: a meta-analysis. Br Med Bull. doi:10.1093/bmb/ldab015
https://www.ncbi.nlm.nih.gov/pubmed/34296741
Parsons, R. D., Bergmann, S., Wiech, K., & Terhune, D. B. (2021).
Direct verbal suggestibility as a predictor of placebo hypoalgesia responsiveness. Psychosom Med. doi:10.1097/PSY.0000000000000977
https://www.ncbi.nlm.nih.gov/pubmed/34297008
Sedano, R., Hogan, M., Nguyen, T. M., Chang, J., Zou, G. Y., Macdonald, J. K., Vande Casteele, N., Hanzel, J., Crowley, E., Battat, R., Dulai, P. S., Singh, S., D’Haens, G., Sandborn, W., Feagan, B. G., Ma, C. & Jairath, V. (2021).
Systematic review and Meta-analysis: Clinical, Endoscopic, Histologic and Safety Placebo Rates in Induction and Maintenance trials of Ulcerative Colitis. J Crohns Colitis. doi:10.1093/ecco-jcc/jjab135
https://www.ncbi.nlm.nih.gov/pubmed/34309658
Shephard, A., & Barrett, S. P. (2021).
The impacts of caffeine administration, expectancies, and related stimuli on coffee craving, withdrawal, and self-administration. J Psychopharmacol, 2698811211032447. doi:10.1177/02698811211032447
https://www.ncbi.nlm.nih.gov/pubmed/34278878
Sung, Y. K., & Lee, Y. H. (2021).
Placebo and nocebo responses in randomized controlled trials of non-tumor necrosis factor biologics and Janus kinase inhibitors in patients with active rheumatoid arthritis showing insufficient response to tumor necrosis factor inhibitors: A meta-analysis. Z Rheumatol. doi:10.1007/s00393-021-01047-7
https://www.ncbi.nlm.nih.gov/pubmed/34241691
Swerts, D. B., Benedetti, F., & Peres, M. F. P. (2021).
Different routes of administration in chronic migraine prevention lead to different placebo responses: a meta-analysis. Pain. doi:10.1097/j.pain.0000000000002365
https://www.ncbi.nlm.nih.gov/pubmed/34252914
Tarpey, T., Petkova, E., Ciarleglio, A., & Ogden, R. T. (2021).
Extracting scalar measures from functional data with applications to placebo response. Stat Interface, 14(3), 255-265. doi:10.4310/20-sii633
https://www.ncbi.nlm.nih.gov/pubmed/34316322
Weng, L., Peerdeman, K. J., Della Porta, D., van Laarhoven, A. I. M., & Evers, A. W. M. (2021).
Can placebo and nocebo effects generalize within pain modalities and across somatosensory sensations? Pain. doi:10.1097/j.pain.0000000000002390
https://www.ncbi.nlm.nih.gov/pubmed/34232926
Xiao, M., Ying, J., Zhao, Y., Li, Q., Zhao, Y., Gao, R., & Lu, F. (2021).
Developing Placebos for Clinical Research in Traditional Chinese Medicine: Assessing Organoleptic Properties of Three Dosage Forms (Oral Liquid, Capsule and Granule). Front Pharmacol, 12, 673729. doi:10.3389/fphar.2021.673729
https://www.ncbi.nlm.nih.gov/pubmed/34220509
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