Today we present 28 new placebo and nocebo research papers, book chapters, comments and abstracts identified during May 2024. As usual, they are based on new PUBMED publication using the search terms „placebo“ and „nocebo“ and are hand-selected from more than 1182 new publications during the preceding month. Previously published monthly updates can be found in our archive. Todays selection as well as all previously identified papers will also go into our placebo research library that currently contains around 5,400 relevant papers. If you would like to get access to the full database, please register for our newsletter and provide us with your email address and affiliation.
Ambrozy, C. A., Hawes, N. E., Hayden, O. L., Sortz, I., & Malek, M. H. (2024).
Caffeine Expectancy Does Not Influence the Physical Working Capacity at the Fatigue Threshold. J Strength Cond Res, 38(6), 1056-1062. doi:10.1519/JSC.0000000000004742
https://www.ncbi.nlm.nih.gov/pubmed/38781467
Asan, L., Kleine-Borgmann, J., Bozkurt, B., Frank, B., Köhrmann, M., Kleinschnitz, C., & Bingel, U. (2024).
Media coverage of COVID-19 vaccination-associated cerebral venous sinus thrombosis was followed by a surge in emergency presentations due to headache – observations from a university hospital in Germany. Frontiers in Psychiatry, 15. doi:10.3389/fpsyt.2024.1378472
https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1378472
Balsby, I. M., Nielsen, S. M., Christensen, R., Henriksen, M., Dahl, L. U., Berg, J. I., Tarp, S., Kroon, F., Kloppenburg, M., Zhang, W., Hunter, D. J., Bliddal, H. & Dossing, A. (2024).
Comparative effectiveness of different placebos and comparator groups for hand osteoarthritis exploring the impact of contextual factors: A systematic review and meta-analysis of randomised trials. Osteoarthritis Cartilage. doi:10.1016/j.joca.2024.02.947
https://www.ncbi.nlm.nih.gov/pubmed/38679284
Bschor, T., Nagel, L., Unger, J., Schwarzer, G., & Baethge, C. (2024).
Differential Outcomes of Placebo Treatment Across 9 Psychiatric Disorders: A Systematic Review and Meta-Analysis. JAMA Psychiatry. doi:10.1001/jamapsychiatry.2024.0994
https://www.ncbi.nlm.nih.gov/pubmed/38809560
Colloca, L., Mocci, E., Wang, Y., Massalee, R., Chen, S., White, J., Johnson, K., Patron Fidalgo, G. M., Wilson, G. M., Goldman, D. & Dorsey, S. G. (2024).
Transcriptomic Profiles Associated with Experimental Placebo Effects in Chronic Pain. Clin Pharmacol Ther. doi:10.1002/cpt.3286
https://www.ncbi.nlm.nih.gov/pubmed/38711244
Devinsky, O., Hyland, K., Loftus, R., Nortvedt, C., & Nabbout, R. (2024).
Placebo response in patients with Dravet syndrome: Post-hoc analysis of two clinical trials. Epilepsy Behav, 156, 109805. doi:10.1016/j.yebeh.2024.109805
https://www.ncbi.nlm.nih.gov/pubmed/38677101
Evers, A. W. M., Van Lennep, J. P. A., & Ten Broek, R. P. G. (2024).
[Placebo procedures in the operating room: necessary or an unnecessary risk for the patient?]. Ned Tijdschr Geneeskd, 168.
https://www.ncbi.nlm.nih.gov/pubmed/38804997
Goli, F. (2024).
Biosemiotic medicines: Symbolic formulations for placebo enhancements. J Educ Health Promot, 13, 156. doi:10.4103/jehp.jehp_1888_23
https://www.ncbi.nlm.nih.gov/pubmed/38784294
Huynh, K. N., Rouse-Watson, S., Chu, J., Lane, A. S., & Cyna, A. M. (2024).
Unheard and unseen: The hidden impact of nocebo communication in the Intensive Care Unit. J Intensive Care Soc, 25(2), 128-130. doi:10.1177/17511437231214148
https://www.ncbi.nlm.nih.gov/pubmed/38737306
Jaltare, K. P., Meyers, E., & Torta, D. M. (2024).
The Role of Pain Expectations in the Development of Secondary Pinprick Hypersensitivity: Behavioral-Neurophysiological Evidence and the Role of Pain-Related Fear. J Pain, 104567. doi:10.1016/j.jpain.2024.104567
https://www.ncbi.nlm.nih.gov/pubmed/38750990
Karacaoglu, M., Peerdeman, K. J., Karch, J. D., van Middendorp, H., & Evers, A. W. M. (2024).
Nocebo hyperalgesia and other expectancy-related factors in daily fibromyalgia pain: Combining experimental and electronic diary methods. J Psychosom Res, 182, 111676. doi:10.1016/j.jpsychores.2024.111676
https://www.ncbi.nlm.nih.gov/pubmed/38688078
Klauss, H., Kunkel, A., Mussgens, D., Haaker, J., & Bingel, U. (2024).
Learning by observing: a systematic exploration of modulatory factors and the impact of observationally induced placebo and nocebo effects on treatment outcomes. Front Psychol, 15, 1293975. doi:10.3389/fpsyg.2024.1293975
https://www.ncbi.nlm.nih.gov/pubmed/38699574
Li, X., Baser, R. E., Bryl, K., Amann, L., Chimonas, S., & Mao, J. J. (2024).
How does pretreatment expectancy influence pain outcomes with electroacupuncture and battlefield acupuncture in cancer survivors?: Pretreatment expectancy and pain reduction by acupuncture. Integr Med Res, 13(2), 101040. doi:10.1016/j.imr.2024.101040
https://www.ncbi.nlm.nih.gov/pubmed/38721341
Merlo Pich, E. (2024).
Placebo response in RCT for antidepressant may not always be the ‘villain’ to fight: are KOR antagonists possibly affecting the intrinsic placebo response? Neuropsychopharmacology. doi:10.1038/s41386-024-01878-3
https://www.ncbi.nlm.nih.gov/pubmed/38783111
Nasiri-Dehsorkhi, H., Vaziri, S., Esmaillzadeh, A., & Adibi, P. (2024).
Negative expectations (nocebo phenomenon) in clinical interventions: A scoping review. J Educ Health Promot, 13, 106. doi:10.4103/jehp.jehp_269_23
https://www.ncbi.nlm.nih.gov/pubmed/38726093
Ooghe, A., Liu, X., Robbins, S., Eyles, J. P., Deveza, L. A., Branders, S., Clermont, F., Pereira, A., & Hunter, D. J. (2024).
Report of similar placebo response in one internet versus onsite randomised controlled trials from the literature. Osteoarthr Cartil Open, 6(2), 100474. doi:10.1016/j.ocarto.2024.100474
https://www.ncbi.nlm.nih.gov/pubmed/38737983
Ortiz-Sanchez, D., Bravo-Sanchez, A., Ramirez-delaCruz, M., Abian, P., & Abian-Vicen, J. (2024).
Placebo Effect of Caffeine on Physiological Parameters and Physical Performance. Nutrients, 16(10). doi:10.3390/nu16101405
https://www.ncbi.nlm.nih.gov/pubmed/38794643
Poulter, D., Miciak, M., Durham, J., Palese, A., & Rossettini, G. (2024).
Don’t be a nocebo! Why healthcare organizations should value patients’ expectations. Front Psychol, 15, 1393179. doi:10.3389/fpsyg.2024.1393179
https://www.ncbi.nlm.nih.gov/pubmed/38694433
Raghuraman, N., White, J. N., Watson, L., Bellei-Rodriguez, C. E., Shafir, R., Wang, Y., & Colloca, L. (2024).
Neuropsychological mechanisms of observational learning in human placebo effects. Psychopharmacology (Berl). doi:10.1007/s00213-024-06608-7
https://www.ncbi.nlm.nih.gov/pubmed/38743108
Saueressig, T., Owen, P. J., Pedder, H., Arora, N. K., Simons, M., Kaczorowski, S., Miller, C. T., Donath, L. & Belavy, D. L. (2024).
Boosting treatment outcomes via the patient-practitioner relationship, treatment-beliefs or therapeutic setting. A systematic review with meta-analysis of contextual effects in chronic musculoskeletal pain. J Orthop Sports Phys Ther, 1-51. doi:10.2519/jospt.2024.12259
https://www.ncbi.nlm.nih.gov/pubmed/38687160
Schenk, L. A., Fadai, T., & Buchel, C. (2024).
How side effects can improve treatment efficacy: a randomized trial. Brain. doi:10.1093/brain/awae132
https://www.ncbi.nlm.nih.gov/pubmed/38701224
Schmidt, T., Meyerhoff, N., Meller, S., Twele, F., Charalambous, M., Berk, B. A., Law, T. H., Packer, R. M. A., Zanghi, B., Pan, Y., Fischer, A. & Volk, H. A. (2024).
Re-evaluating the placebo response in recent canine dietary epilepsy trials. BMC Vet Res, 20(1), 224. doi:10.1186/s12917-024-04066-z
https://www.ncbi.nlm.nih.gov/pubmed/38783265
Schwarting, R. K. W., Wohr, M., Engler, H., Sungur, A. O., & Schedlowski, M. (2024).
Behaviorally conditioned effects of psychoactive drugs in experimental animals: What we have learned from nearly a century of research and what remains to be learned. Neurosci Biobehav Rev, 162, 105721. doi:10.1016/j.neubiorev.2024.105721
https://www.ncbi.nlm.nih.gov/pubmed/38754716
Shetty, A. C., Sivinski, J., Cornell, J., McCracken, C., Sadzewicz, L., Mahurkar, A., Wang, X. Q., Colloca, L., Lin, W., Pilli, N., Kane, M. A. & Seneviratne, C. (2024).
Peripheral blood transcriptomic profiling of molecular mechanisms commonly regulated by binge drinking and placebo effects. Sci Rep, 14(1), 10733. doi:10.1038/s41598-024-56900-x
https://www.ncbi.nlm.nih.gov/pubmed/38730024
Skvortsova, A., Meeuwis, S. H., Derksen, S., Kerkkanen, K., Sutter, E., Evers, A. W. M., & Veldhuijzen, D. S. (2024).
The role of self-reported and physiological stress in nocebo hyperalgesia. Biol Psychol, 190, 108818. doi:10.1016/j.biopsycho.2024.108818
https://www.ncbi.nlm.nih.gov/pubmed/38762001
Tang, B., Livesey, E., & Colagiuri, B. (2024).
The downside to choice: instrumental control increases conditioned nocebo hyperalgesia. Pain. doi:10.1097/j.pain.0000000000003251
https://www.ncbi.nlm.nih.gov/pubmed/38709490
Won, J., Han, J. Y., Ji, Y. J., Ha, D., Han, B. J., & Lee, H. (2024).
Drug trials are more likely to disclose full placebo control information than non-drug trials: A cross-sectional study of participant information leaflets of placebo-controlled trials. Integr Med Res, 13(2), 101043. doi:10.1016/j.imr.2024.101043
https://www.ncbi.nlm.nih.gov/pubmed/38779540
Yang, M., Li, Q. S., Baser, R. E., Li, X., Hou, J., & Mao, J. J. (2024).
Nocebo expectations rather than placebo expectations affect topical pain relief: A randomized clinical trial. Biomed Pharmacother, 175, 116728. doi:10.1016/j.biopha.2024.116728
https://www.ncbi.nlm.nih.gov/pubmed/38733772
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