Today we present 28 new placebo and nocebo research papers, book chapters, comments and abstracts identified during September 2024. As usual, they are based on new PUBMED publication using the search terms „placebo“ and „nocebo“ and are hand-selected from more than 1017 new publications during the preceding month. Previously published monthly updates can be found in our archive. Todays selection as well as all previously identified papers will also go into our placebo research library that currently contains around 5,400 relevant papers. If you would like to get access to the full database, please register for our newsletter and provide us with your email address and affiliation.
Albazee, E., Alharran, A. M., & Alzayed, M. M. (2024).
The effect of open-label placebo on allergic rhinitis symptoms: A systematic review and meta-analysis of randomized controlled trials. Int Forum Allergy Rhinol. doi:10.1002/alr.23444
https://www.ncbi.nlm.nih.gov/pubmed/39212086
Ashar, Y. K., Sun, M., Knight, K., Flood, T. F., Anderson, Z., Kaptchuk, T. J., & Wager, T. D. (2024).
Open-Label Placebo Injection for Chronic Back Pain With Functional Neuroimaging: A Randomized Clinical Trial. JAMA Netw Open, 7(9), e2432427. doi:10.1001/jamanetworkopen.2024.32427
https://www.ncbi.nlm.nih.gov/pubmed/39259542
Bentin, J. M., Arendt-Nielsen, L., & Bihlet, A. R. (2024).
Placebo effect in clinical practice. Ugeskr Laeger, 186(34). doi:10.61409/V02240121
https://www.ncbi.nlm.nih.gov/pubmed/39234882
Chen, B., Goldstein, N., Dziubek, J., Sundai, A., Zhao, S., Harrahill, A., Choi, S., Prevosto, V. & Wang, F. (2024).
Reverse-engineering placebo analgesia. Curr Biol, 34(18), 4261-4271 e4265. doi:10.1016/j.cub.2024.08.004
https://www.ncbi.nlm.nih.gov/pubmed/39241777
Clark, A. (2024).
Hacking the Predictive Mind. Entropy, 26(8). doi:10.3390/e26080677
https://www.ncbi.nlm.nih.gov/pubmed/39202147
Cusin, C., Dillon, D. G., Belleau, E., Normandin, M. D., Petibon, Y., El-Fakri, G., Dhaynaut, M., Hooker, J., Kaptchuk, T., McKee, M., Hayden, E., Meyer, A., Jahan, A., Origlio, J., Ang, Y. S., Brunner, D., Kang, M., Long, Y., Fava, M. & Pizzagalli, D. A. (2024).
Novel multi-modal methodology to investigate placebo response in major depressive disorder. J Affect Disord, 368, 1-7. doi:10.1016/j.jad.2024.08.226
https://www.ncbi.nlm.nih.gov/pubmed/39233242
Daniali, H., Hunsbeth, P. L., & Flaten, M. A. (2024).
Effects of open and hidden administration of treatment-related information; a multi-experiment study. Psychol Health, 1-29. doi:10.1080/08870446.2024.2392820
https://www.ncbi.nlm.nih.gov/pubmed/39205487
Gorner, K. J., Spotts, E. K., & Geers, A. L. (2024).
Identifying the psychological effects of nocebo education: results from two pre-registered experiments. J Behav Med. doi:10.1007/s10865-024-00520-3
https://www.ncbi.nlm.nih.gov/pubmed/39306633
Gousset, S., Cayrol, T., Papleux, M., Meulders, A., Mouraux, A., & van den Broeke, E. N. (2024).
Studying the effect of expectations on high-frequency electrical stimulation-induced pain and pinprick hypersensitivity. J Pain, 104682. doi:10.1016/j.jpain.2024.104682
https://www.ncbi.nlm.nih.gov/pubmed/39306061
Guevarra, D. A., Kross, E., & Moser, J. S. (2024).
Harnessing placebo effects to regulate emotions. In J. J. Gross & B. Q. Ford (Eds.), Handbook of emotion regulation (3 ed., pp. 112-118): The Guilford Press.
https://static1.squarespace.com/static/66a2e8a9f91d692beab88cbd/t/66bc01c0649f2a25ac47be85/1723597248350/Guevarra%2C+Kross%2C+%26+Moser+%282024%29+-+Hndbk+of+ER+-+Ch.pdf
Horvath, A., Aranyosy, B., Drozdovszky, O., Szabo, A., & Koteles, F. (2024).
Placebo and nocebo interventions impact perceived but not actual proprioceptive accuracy. PLoS One, 19(8), e0307072. doi:10.1371/journal.pone.0307072
https://www.ncbi.nlm.nih.gov/pubmed/39213316
Jensen, K. B. (2024).
Placebo effects beyond dopamine. PLoS Biol, 22(9), e3002812. doi:10.1371/journal.pbio.3002812
https://www.ncbi.nlm.nih.gov/pubmed/39321143
Kunkel, A., Asan, L., Kruger, I., Erfurt, C., Ruhnau, L., Caliskan, E. B., Hackert, J., Wiech, K., Schmidt, K. & Bingel, U. (2024).
Dopamine has no direct causal role in the formation of treatment expectations and placebo analgesia in humans. PLoS Biol, 22(9), e3002772. doi:10.1371/journal.pbio.3002772
https://www.ncbi.nlm.nih.gov/pubmed/39316644
Li, J., Xiao, C., Li, T., Duan, Y., Jiang, Y., Shi, L., Hong, X., Geng, W., Hu, J., Wang, Y., Dai, B., Cao, J. & Wei, J. (2024).
Treatment expectations of patients and clinicians: a cross-sectional study. Front Psychiatry, 15, 1447405. doi:10.3389/fpsyt.2024.1447405
https://www.ncbi.nlm.nih.gov/pubmed/39238937
Meyrose, A. K., Basedow, L. A., Hirsing, N., Buchweitz, O., Rief, W., & Nestoriuc, Y. (2024).
Assessment of treatment expectations in people with suspected endometriosis: A psychometric analysis. F1000Res, 13, 174. doi:10.12688/f1000research.145377.2
https://www.ncbi.nlm.nih.gov/pubmed/39328391
Mostafa, R., McNair, N. A., Tan, W., Saunders, C., Colagiuri, B., & Barnes, K. (2024).
Interpersonal physiological and psychological synchrony predict the social transmission of nocebo hyperalgesia between individuals. Commun Psychol, 2(1), 33. doi:10.1038/s44271-024-00069-6
https://www.ncbi.nlm.nih.gov/pubmed/39242740
Munoz Laguna, J., Lee, H., Poltavskiy, E., Kim, J., & Bang, H. (2024).
Participant’s treatment guesses and adverse events in back pain trials: Nocebo in action? Clin Trials, 17407745241276124. doi:10.1177/17407745241276124
https://www.ncbi.nlm.nih.gov/pubmed/39275808
Nadinda, P. G., van Laarhoven, A. I. M., Van den Bergh, O., Vlaeyen, J. W. S., Peters, M. L., & Evers, A. W. M. (2024).
Expectancies and avoidance: Towards an integrated model of chronic somatic symptoms. Neuroscience & Biobehavioral Reviews, 164, 105808. doi:https://doi.org/10.1016/j.neubiorev.2024.105808
https://www.sciencedirect.com/science/article/pii/S014976342400277X
Pei, M., Gibson, C. J., Grady, D., & Huang, A. J. (2024).
Addressing the Impact of High Placebo Response in Hot Flash Treatment Trials. Am J Obstet Gynecol. doi:10.1016/j.ajog.2024.09.012
https://www.ncbi.nlm.nih.gov/pubmed/39278340
Previtali, D., Albanese, J., Romandini, I., Merli, G., Taraballi, F., & Filardo, G. (2024).
Placebo Effect in the Treatment of Patellar Tendinopathy and Its Influencing Factors: Systematic Review With Meta-analysis and Meta Regression of Randomized Controlled Trials. Orthop J Sports Med, 12(8), 23259671241258477. doi:10.1177/23259671241258477
https://www.ncbi.nlm.nih.gov/pubmed/39221039
Rief, W., & Wilhelm, M. (2024).
Nocebo and Placebo Effects and Their Implications in Psychotherapy. Psychother Psychosom, 1-6. doi:10.1159/000540791
https://www.ncbi.nlm.nih.gov/pubmed/39217983
Riegner, G., Dean, J., Wager, T. D., & Zeidan, F. (2024).
Mindfulness meditation and placebo modulate distinct multivariate neural signatures to reduce pain. Biol Psychiatry. doi:10.1016/j.biopsych.2024.08.023
https://www.ncbi.nlm.nih.gov/pubmed/39216636
Roy, S., Edwards, M. A., Petrie, K. J., Gamble, G. D., & Jacques, E. (2024).
A Possible Nocebo Effect in Children Following the Flint Water Crisis: Evidence From Schoolteacher Perceptions and Neuropsychological Evaluations. Disaster Med Public Health Prep, 18, e115. doi:10.1017/dmp.2024.106
https://www.ncbi.nlm.nih.gov/pubmed/39291310
Saunders, C., Tan, W., Faasse, K., Colagiuri, B., Sharpe, L., & Barnes, K. (2024).
The effect of social learning on the nocebo effect: a systematic review and meta-analysis with recommendations for the future. Health Psychol Rev, 1-20. doi:10.1080/17437199.2024.2394682
https://www.ncbi.nlm.nih.gov/pubmed/39205378
Schaefer, M., Kuhnel, A., & Enge, S. (2024).
Open-label placebos reduce weight in obesity: a randomized controlled trial. Sci Rep, 14(1), 21311. doi:10.1038/s41598-024-69866-7
https://www.ncbi.nlm.nih.gov/pubmed/39266589
Staudacher, H. M., & Putkonen, L. T. (2024).
Nocebo, gut disorders, and diet. Lancet Gastroenterol Hepatol, 9(10), 909. doi:10.1016/S2468-1253(24)00281-4
https://www.ncbi.nlm.nih.gov/pubmed/39243771
Wang, Y. T., Zhang, P. M., Dong, Y., Fan, B. C., & Lu, L. M. (2024).
Analysis of placebo effect of acupuncture. Zhen Ci Yan Jiu, 49(8), 875-879. doi:10.13702/j.1000-0607.20230390
https://www.ncbi.nlm.nih.gov/pubmed/39318318
Xue, P., Qin, H., Qin, D., Shi, Y., Li, H., Luo, T., Shi, C., Wang, Y., Zhao, Z., Cao, W., Zou, Z., Yang, Q., Jin, R., Li, J., & Xiao, X. (2024).
The Effect of Placebo on Pruritus in Patients with Chronic Urticaria: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials. Clin Drug Investig. doi:10.1007/s40261-024-01389-5
https://www.ncbi.nlm.nih.gov/pubmed/39242484
Placebo in the media
Religion is simply a powerful placebo – offering priests a sense of ritual, but little else. By Colin Brewer in The Skeptic:
https://www.skeptic.org.uk/2024/09/religion-is-simply-a-powerful-placebo-offering-priests-a-sense-of-ritual-but-little-else/
Download PDF here.