Today we present 20 new placebo and nocebo research papers, book chapters, comments and abstracts identified during October 2022. As usual, they are based on new PUBMED publication using the search terms „placebo“ and „nocebo“ and are hand-selected from more than 1051 new publications during the preceding month. Previously published monthly updates can be found in our archive. Todays selection as well as all previously identified papers will also go into our placebo research library that currently contains nearly 5,000 relevant papers. If you would like to get access to the full database, please register for our newsletter and provide us with your email address and affiliation.
Amanzio, M., Cipriani, G. E., & Mitsikostas, D. D. (2022).
The nocebo phenomenon in the COVID-19 pandemic: a nocebodemic effect. Expert Rev Clin Pharmacol, 1-6. doi:10.1080/17512433.2022.2142115
https://www.ncbi.nlm.nih.gov/pubmed/36305792
Chin, Y. H., Ng, C. H., Chew, N. W., Kong, G., Lim, W. H., Tan, D. J. H., Chan, K. E., Tang, A., Huang, D. Q., Chan, M. Y., Figtree, G., Wang, J. W., Shabbir, A., Khoo, C. M., Wong, V. W., Young, D. Y., Siddiqui, M. S., Noureddin, M., Sanyal, A., Cummings, D. E., Syn, N. & Muthiah, M. D. (2022).
The placebo response rate and nocebo events in obesity pharmacological trials. A systematic review and meta-analysis. EClinicalMedicine, 54, 101685. doi:10.1016/j.eclinm.2022.101685
https://www.ncbi.nlm.nih.gov/pubmed/36193169
Darbellay, C., Magnin, S., Haidar Ahmad, A., Wolff, A., Serratrice, J., & Coen, M. (2022).
[Healing communication: Therapeutic communication in internal medicine]. Rev Med Suisse, 18(801), 2026-2029. doi:10.53738/REVMED.2022.18.801.2026
https://www.ncbi.nlm.nih.gov/pubmed/36314093
Fraguas, D., Díaz-Caneja, C. M., Pina-Camacho, L., Umbricht, D., & Arango, C. (2022).
Correction to: Predictors of Placebo Response in Pharmacological Clinical Trials of Negative Symptoms in Schizophrenia: A Meta-regression Analysis. Schizophr Bull. doi:10.1093/schbul/sbac172
https://www.ncbi.nlm.nih.gov/pubmed/36315443
Gerke, L., Ladwig, S., Pauls, F., Trachsel, M., Harter, M., & Nestoriuc, Y. (2022).
Optimized Informed Consent for Psychotherapy: Protocol for a Randomized Controlled Trial. JMIR Res Protoc, 11(9), e39843. doi:10.2196/39843
https://www.ncbi.nlm.nih.gov/pubmed/36178713
Hohenschurz-Schmidt, D., Draper-Rodi, J., Vase, L., Scott, W., McGregor, A., Soliman, N., MacMillan, A., Olivier, A., Cherian, C. A., Corcoran, D., Abbey, H., Freigang, S., Chan, J., Phalip, J., Sorensen, L. N., Delafin, M., Baptista, M., Medforth, N. R., Ruffini, N., Andresen, S. S., Ytier, S., Ali, D., Hobday, H., Ngurah Agung Adhiyoga Santosa, A. A., Vollert, J. & Rice, A. S. C. (2022).
Blinding and sham control methods in trials of physical, psychological, and self-management interventions for pain (article II): a meta-analysis relating methods to trial results. Pain. doi:10.1097/j.pain.0000000000002730
https://www.ncbi.nlm.nih.gov/pubmed/36271798
Iwama, Y., Takamoto, K., Hibi, D., Nishimaru, H., Matsumoto, J., Setogawa, T., & Nishijo, H. (2022).
Young female participants show blunted placebo effects associated with blunted responses to a cue predicting a safe stimulus in the right dorsolateral prefrontal cortex. Front Neurosci, 16, 1001177. doi:10.3389/fnins.2022.1001177
https://www.ncbi.nlm.nih.gov/pubmed/36263366
Kirsch, D. E., Le, V., Kosted, R., Fromme, K., & Lippard, E. T. C. (2022).
Neural underpinnings of expecting alcohol: Placebo alcohol administration alters nucleus accumbens resting state functional connectivity. Behav Brain Res, 437, 114148. doi:10.1016/j.bbr.2022.114148
https://www.ncbi.nlm.nih.gov/pubmed/36206822
Klosowska, J., Bajcar, E. A., Bieniek, H., Braczyk, J., Joshanloo, M., Mattarozzi, K., Bagnis, A., Ponten, M., Lalouni, M., Geers, A. L., Clemens, K. S., Park, J., Choi, G., Choi, Y. K., Jung, W., Son, E., Yoon, H. Y. & Babel, P. (2022).
Development and cross-national investigation of a model explaining participation in WHO-recommended and placebo behaviours to prevent COVID-19 infection. Sci Rep, 12(1), 17704. doi:10.1038/s41598-022-17303-y
https://www.ncbi.nlm.nih.gov/pubmed/36271008
Lin Tay, P. W., Ng, C. H., Lin, S. Y., Chin, Y. H., Xiao, J., Lim, W. H., Lim, S. Y., Fu, C. E., Chan, K. E., Quek, J., Hao Tan, D. J., Chew, N., Syn, N., Keitoku, T., Tamaki, N., Siddiqui, M. S., Noureddin, M., Muthiah, M., Huang, D. Q. & Loomba, R. (2022).
Placebo Adverse Events in Non-Alcoholic Steatohepatitis Clinical Trials. A Pooled Analysis of 2,944 Participants. Am J Gastroenterol. doi:10.14309/ajg.0000000000002042
https://www.ncbi.nlm.nih.gov/pubmed/36191268
Nedrud, M. A., Chaudhry, M., Middleton, M. S., Moylan, C. A., Lerebours, R., Luo, S., Farjat, A., Guy, C., Loomba, R., Abdelmalek, M. F., Sirlin, C. B. & Bashir, M. R. (2022).
MRI Quantification of Placebo Effect in Nonalcoholic Steatohepatitis Clinical Trials. Radiology, 220743. doi:10.1148/radiol.220743
https://www.ncbi.nlm.nih.gov/pubmed/36318027
Nissen, S. E. (2022).
When Is a Placebo Not a Placebo. JAMA Cardiol. doi:10.1001/jamacardio.2022.3698
https://www.ncbi.nlm.nih.gov/pubmed/36287549
Nohr, A. K., Forsingdal, A., Moltke, I., Howes, O. D., Vitezic, M., Albrechtsen, A., & Dalby, M. (2022).
Polygenic heterogeneity in antidepressant treatment and placebo response. Transl Psychiatry, 12(1), 456. doi:10.1038/s41398-022-02221-4
https://www.ncbi.nlm.nih.gov/pubmed/36309483
O’Riordan, S. F., Bishop, D. J., Halson, S. L., & Broatch, J. R. (2022).
Compression-induced improvements in post-exercise recovery are associated with enhanced blood flow, and are not due to the placebo effect. Sci Rep, 12(1), 16762. doi:10.1038/s41598-022-21029-2
https://www.ncbi.nlm.nih.gov/pubmed/36202885
Sharma, T., Ma, C., Sedano, R., Hanzel, J., McDonald, C., Hogan, M., Kochhar, G. S., Narula, N., Peyrin-Biroulet, L., Danese, S., MacDonald, J. K. & Jairath, V. (2022).
Placebo response rates in randomized controlled trials for perianal Crohn’s disease: A systematic review and meta-analysis. J Crohns Colitis. doi:10.1093/ecco-jcc/jjac160
https://www.ncbi.nlm.nih.gov/pubmed/36271904
Svobodova, M., Jacob, N., Hood, K., Gillies, K., Hale, R., Bostock, J., Bower, P., Edwards, A., Farthing, P., Rawlinson, S., Treweek, S. & Howick, J. (2022).
Developing principles for sharing information about potential trial intervention benefits and harms with patients: report of a modified Delphi survey. Trials, 23(1), 863. doi:10.1186/s13063-022-06780-1
https://www.ncbi.nlm.nih.gov/pubmed/36209242
Wager, T. D., & Jung, H. (2022).
Unpacking placebo and working memory training effects on cognitive performance. Proc Natl Acad Sci U S A, 119(42), e2214268119. doi:10.1073/pnas.2214268119
https://www.ncbi.nlm.nih.gov/pubmed/36197960
Wen, X., Luo, J., Mai, Y., Li, Y., Cao, Y., Li, Z., Han, S., Fu, Q., Zheng, Q., Ding, C., Zhu, Z. & Li, L. (2022).
Placebo Response to Oral Administration in Osteoarthritis Clinical Trials and Its Associated Factors: A Model-Based Meta-analysis. JAMA Netw Open, 5(10), e2235060. doi:10.1001/jamanetworkopen.2022.35060
https://www.ncbi.nlm.nih.gov/pubmed/36215072
Wise, J., Ingrosso, M. R., Ianiro, G., Black, C. J., Ford, A. C., & Lacy, B. E. (2022).
Response and Adverse Event Rates with Placebo in Gastroparesis: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. doi:10.1016/j.cgh.2022.09.033
https://www.ncbi.nlm.nih.gov/pubmed/36270614
Yoon, J. H. (2022).
A Placebo Effect on MRI Proton Density Fat Fraction in Nonalcoholic Steatohepatitis Trials. Radiology, 222295. doi:10.1148/radiol.222295
https://www.ncbi.nlm.nih.gov/pubmed/36318034
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