Today we present 29 new placebo research papers, comments and abstracts identified during February 2017. As usual, they are based on new PUBMED publication using the search terms „placebo“ and „nocebo“ and are hand-selected from more than 703 new publications during the preceding month. Previously published monthly updates can be found in our archive. Todays selection as well as all previously identified papers will also go into our placebo research library that currently contains more than 3,400 relevant papers. If you would like to get access to the full database, please register for our newsletter and provide us with your email address and affiliation.
Birkhäuer, J., Gaab, J., Kossowsky, J., Hasler, S., Krummenacher, P., Werner, C., Gerger, H. (2017)
Trust in the health care professional and health outcome: A meta-analysis. PLoS One. 12(2):e0170988. doi: 10.1371/journal.pone.0170988.
https://www.ncbi.nlm.nih.gov/pubmed/28170443
Blease, C.R., Bishop, F.L., Kaptchuk, T.J. (2017)
Informed consent and clinical trials: where is the placebo effect? BMJ. 356:j463. doi: 10.1136/bmj.j463.
https://www.ncbi.nlm.nih.gov/pubmed/28159769
de Barra, M. (2017)
Reporting bias inflates the reputation of medical treatments: A comparison of outcomes in clinical trials and online product reviews. Soc Sci Med. doi: 10.1016/j.socscimed.2017.01.033. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28190628
Desselas, E., Pansieri, C., Leroux, S., Bonati, M., Jacqz-Aigrain, E. (2017)
Drug versus placebo randomized controlled trials in neonates: A review of ClinicalTrials.gov registry. PLoS One.12(2):e0171760. doi:10.1371/journal.pone.0171760.
https://www.ncbi.nlm.nih.gov/pubmed/28192509
Dodd, S., Dean, O.M., Vian, J., Berk, M. (2017)
A Review of the Theoretical and Biological Understanding of the Nocebo and Placebo Phenomena. Clin Ther. doi: 10.1016/j.clinthera.2017.01.010. [Epub ahead of print] Review.
https://www.ncbi.nlm.nih.gov/pubmed/28161116
Esch, T., Winkler, J., Auwärter, V., Gnann, H., Huber, R., Schmidt, S. (2017)
Neurobiological Aspects of Mindfulness in Pain Autoregulation: Unexpected Results from a Randomized-Controlled Trial and Possible Implications for Meditation Research. Front Hum Neurosci.10:674. doi:10.3389/fnhum.2016.00674.
https://www.ncbi.nlm.nih.gov/pubmed/28184192
Giannouli, V. (2017)
Memory and Hashimoto’s thyroiditis under levothyroxine treatment: is there a placebo or nocebo effect? Endocrine. doi: 10.1007/s12020-017-1262-0. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28205014
Gross, L. (2017)
Putting placebos to the test. PLoS Biol. 15(2):e2001998. doi: 10.1371/journal.pbio.2001998.
https://www.ncbi.nlm.nih.gov/pubmed/28222121
Gueorguieva, R., Chekroud, A.M., Krystal, J.H. (2017)
Trajectories of relapse in randomised, placebo-controlled trials of treatment discontinuation in major depressive disorder: an individual patient-level data meta-analysis. Lancet Psychiatry. doi: 10.1016/S2215-0366(17)30038-X. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28189575
Icenhour, A., Labrenz, F., Ritter, C., Theysohn, N., Forsting, M., Bingel, U., Elsenbruch, S. (2017)
Learning by experience? Visceral pain-related neural and behavioral responses in a classical conditioning paradigm. Neurogastroenterol Motil. doi: 10.1111/nmo.13026. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28177183
Ioannidis, J.P. (2017)
Does evidence-based hearsay determine the use of medical treatments? Soc Sci Med. doi: 10.1016/j.socscimed.2017.02.004. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28190627
Jairath, V., Zou, G., Parker, C.E., MacDonald, J.K., Mosli, M.H., AlAmeel, T., Al Beshir, M., AlMadi, M., Al-Taweel, T., Atkinson, N.S., Biswas, S., Chapman, T.P., Dulai, P.S., Glaire, M.A., Hoekman, D., Kherad, O., Koutsoumpas, A., Minas, E., Restellini, S., Samaan, M.A., Khanna, R., Levesque, B.G., D’Haens, G., Sandborn, W.J., Feagan, B.G. (2017)
Systematic review with meta-analysis: placebo rates in induction and maintenance trials of Crohn’s disease. Aliment Pharmacol Ther. doi: 10.1111/apt.13973. [Epub ahead of print] Review.
https://www.ncbi.nlm.nih.gov/pubmed/26746169
John, A.P., Singh, N.M., Nagarajaiah, Andrade, C. (2016)
Impact of an educational module in antidepressant-naive patients prescribed antidepressants for depression: Pilot, proof-of-concept, randomized controlled trial. Indian J Psychiatry. 58(4):425-431. doi: 10.4103/0019-5545.196710.
https://www.ncbi.nlm.nih.gov/pubmed/28197000
Jung, W.M., Lee, Y.S., Wallraven, C., Chae, Y. (2017)
Bayesian prediction of placebo analgesia in an instrumental learning model. PLoS One.12(2):e0172609. doi:10.1371/journal.pone.0172609.
https://www.ncbi.nlm.nih.gov/pubmed/28225816
Kardum, N., Konic Ristic, A., Zec, M., Kojadinovic, M., Petrovic-Oggiano, G., Zekovic, M., Kroon, P.A., Glibetić, M. (2017)
Design, formulation and sensory evaluation of a polyphenol-rich food placebo: an example of aronia juice for food intervention studies. Int J Food Sci Nutr. 1-8. doi:10.1080/09637486.2017.1283682. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28147889
Linden, M. (2017)
Placebo: Unsolved Problems for Science, and Simple Conclusions for Clinical Practice. Am J Psychiatry. 174(2):91-92. doi:10.1176/appi.ajp.2016.16101181.
https://www.ncbi.nlm.nih.gov/pubmed/28142273
Lückemann, L., Unteroberdörster, M., Kirchhof, J., Schedlowski, M., Hadamitzky, M. (2017)
Applications and limitations of behaviorally conditioned immunopharmacological responses. Neurobiol Learn Mem. doi:10.1016/j.nlm.2017.02.012. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28216206
Mahr, A., Golmard, C., Pham, E., Iordache, L., Deville, L., Faure, P. (2017)
Types, frequencies, and burden of nonspecific adverse events of drugs: analysis of randomized placebo-controlled clinical trials. Pharmacoepidemiol Drug Saf. doi: 10.1002/pds.4169. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28176407
Rebelo, E.E. (2015)
Thoughts on Giving Full and Accurate Information. Gen Med (Los Angel) 3: 218. doi:10.4172/2327-5146.1000218.
http://collections.plos.org/open-highlights-placebos
Schienle, A., Höfler, C., Übel, S., Wabnegger, A. (2017)
Emotion-specific nocebo effects: an fMRI study. Brain Imaging Behav. doi: 10.1007/s11682-017-9675-1. [Epub ahead of print]
http://link.springer.com/article/10.1007/s11682-017-9675-1
Tekampe, J., van Middendorp, H., Meeuwis, S.H., van Leusden, J.W., Pacheco-López, G., Hermus, A.R., Evers, A.W. (2017)
Conditioning Immune and Endocrine Parameters in Humans: A Systematic Review. Psychother Psychosom. 86(2):99-107. doi: 10.1159/000449470.
https://www.ncbi.nlm.nih.gov/pubmed/28183096
Waisel, D.B. (2017)
Ethics of research for patients in pain. Curr Opin Anaesthesiol. doi: 10.1097/ACO.0000000000000438. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28151827
Wedi, B., Wieczorek, D., Kapp, A. (2017)
[Placebo effect in clinical trials with allergen-specific immunotherapy with inhalant allergens]. doi: 10.1007/s00105-017-3937-0. [Epub ahead of print] German.
https://www.ncbi.nlm.nih.gov/pubmed/28194483
Comments
to: Carvalho C, Caetano JM, Cunha L, Rebouta P, Kaptchuk TJ, Kirsch I. Open-label placebo treatment in chronic low back pain: a randomized controlled trial. PAIN 2016;157:2766–72. (see Placebo Publications October 2016):
Braillon, A. (2017) Placebo and chronic low back pain: too much in way of expectations, too little in terms of data. Pain. 158(3):535-536. doi:10.1097/j.pain.0000000000000794.
https://www.ncbi.nlm.nih.gov/pubmed/28187104
Mestre, T.A., Ferreira, J.J. (2107) Are placebo pills presented as experimental treatment a true placebo? Pain. 158(3):535. doi:10.1097/j.pain.0000000000000793
https://www.ncbi.nlm.nih.gov/pubmed/28187103
Carvalho, C., Kirsch, I., Kaptchuk, T.J. (2017) Reply. Pain. 158(3):536-537. doi:10.1097/j.pain.0000000000000795.
https://www.ncbi.nlm.nih.gov/pubmed/28187105
Conference Abstracts:
Albu, S., Linsenbardt, H., Meagher, M. (2016) (327) Quantitative EEG markers of pain facilitation by nocebo. J Pain. 17(4S):S57. doi: 10.1016/j.jpain.2016.01.234.
https://www.ncbi.nlm.nih.gov/pubmed/28162564
Kisaalita, N., Robinson, M. (2017) (259) Placebo use among medical providers: patient perceptions and the effects of a mechanism-based educational intervention. J Pain. 17(4S):S40. doi: 10.1016/j.jpain.2016.01.164.
https://www.ncbi.nlm.nih.gov/pubmed/28162492
Pereira, A., Duale, C., Clermont, F., Gramme, P., Branders, S., Gossuin, C., Demolle, D. (2017) (171) Characterization and prediction of placebo responders in peripheral neuropathic patients in a 4-week analgesic clinical trial. J Pain.17(4S):S18. doi: 10.1016/j.jpain.2016.01.074.
https://www.ncbi.nlm.nih.gov/pubmed/28162393