Today we present 40 new placebo research papers, comments and abstracts identified during June 2018. As usual, they are based on new PUBMED publication using the search terms „placebo“ and „nocebo“ and are hand-selected from more than 786 new publications during the preceding month. Previously published monthly updates can be found in our archive. Todays selection as well as all previously identified papers will also go into our placebo research library that currently contains nearly 4,000 relevant papers. If you would like to get access to the full database, please register for our newsletter and provide us with your email address and affiliation.
Ben-Sheetrit, J., Peskin, M., Newcorn, J.H., Daniely, Y., Shbiro, L., Rotem, A., Weizman, A., Manor, I. (2018)
Characterizing the Placebo Response in Adults With ADHD. J Atten Disord. 2018 Jun 1:1087054718780328. doi: 10.1177/1087054718780328. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/29926752
Bernstein, M.H., Brown, W.A. (2018)
The placebo effect in psychiatric practice. Curr Psychiatr. 2017 Nov;16(11):29-34.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003660/
Broelz, E.K., Wolf, S., Schneeweiss, P., Niess, A.M., Enck, P., Weimer, K. (2018)
Increasing effort without noticing: A randomized controlled pilot study about the ergogenic placebo effect in endurance athletes and the role of supplement salience. PLoS One. 2018 Jun 11;13(6):e0198388. doi: 10.1371/journal.pone.0198388. eCollection 2018.
https://www.ncbi.nlm.nih.gov/pubmed/29889868
Castelnuovo, G., Giusti, E.M., Manzoni, G.M., Saviola D, Gabrielli S, Lacerenza M, Pietrabissa G, Cattivelli R, Spatola CAM, Rossi A, Varallo G, Novelli M, Villa V, Luzzati F, Cottini A, Lai C, Volpato E, Cavalera C, Pagnini F, Tesio V, Castelli L, Tavola M, Torta R, Arreghini M, Zanini L, Brunani A, Seitanidis I, Ventura G, Capodaglio P, D’Aniello GE, Scarpina F, Brioschi A, Bigoni M, Priano L, Mauro A, Riva G, Di Lernia D, Repetto C, Regalia C, Molinari E, Notaro P, Paolucci S, Sandrini G, Simpson S, Wiederhold BK, Gaudio S, Jackson JB, Tamburin S, Benedetti F. (2018)
What Is the Role of the Placebo Effect for Pain Relief in Neurorehabilitation? Clinical Implications From the Italian Consensus Conference on Pain in Neurorehabilitation. Front Neurol. 2018 May 18;9:310. doi: 10.3389/fneur.2018.00310. eCollection 2018. Review.
https://www.ncbi.nlm.nih.gov/pubmed/29867723
Chae, Y., Lee, Y.S., Enck, P. (2018)
How Placebo Needles Differ From Placebo Pills? Front Psychiatry. 2018 Jun 5;9:243. doi: 10.3389/fpsyt.2018.00243. eCollection 2018. Review.
https://www.ncbi.nlm.nih.gov/pubmed/29930521
Dodd, S., Walker, A.J., Brnabic, A.J.M., Hong, N., Burns, A., Berk, M. (2018)
Incidence and characteristics of the nocebo response from meta-analyses of the placebo arms of clinical trials of olanzapine for bipolar disorder. Bipolar Disord. 2018 Jun 21. doi: 10.1111/bdi.12662. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/29926533
Duarte, G.S., Rodrigues, F.B., Ferreira, J.J., Costa, J. (2018)
Adverse events with botulinum toxin treatment in cervical dystonia: How much should we blame placebo? Parkinsonism Relat Disord. Jun doi: 10.1016/j.parkreldis.2018.06.017.
https://www.ncbi.nlm.nih.gov/pubmed/29910156
Enck, P. (2018)
Letter: all or nothing-placebo effects in a non-drug clinical trial in IBS. Aliment Pharmacol Ther. 2018 Jul;48(1):105-106. doi: 10.1111/apt.14655.
https://www.ncbi.nlm.nih.gov/pubmed/29882985
Enck, P. (2018)
A Matter of Perspective: Sham Surgery as Effective as Surgery, or Surgery as Uneffective as Sham? Pain Med. 2018 Jun 18. doi: 10.1093/pm/pny127. [Epub ahead of print] PubMed PMID: 29924354.
https://www.ncbi.nlm.nih.gov/pubmed/29924354
Evers, A.W.M., Colloca, L., Blease, C., Annoni, M., Atlas, L.Y., Benedetti, F., Bingel, U., Büchel, C., Carvalho C, Colagiuri B, Crum AJ, Enck P, Gaab J, Geers AL, Howick J, Jensen KB, Kirsch I, Meissner K, Napadow V, Peerdeman KJ, Raz A, Rief W, Vase L, Wager TD, Wampold BE, Weimer K, Wiech K, Kaptchuk TJ, Klinger R, Kelley JM. (2018)
Implications of Placebo and Nocebo Effects for Clinical Practice: Expert Consensus. Psychother Psychosom. 2018 Jun 12:1-7. doi: 10.1159/000490354. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/29895014
Faasse, K., Parkes, B., Kearney, J., Petrie, K.J. (2018)
The Influence of Social Modeling, Gender, and Empathy on Treatment Side Effects. Ann Behav Med. 2018 May 31;52(7):560-570. doi: 10.1093/abm/kax025.
https://academic.oup.com/abm/article/52/7/560/4825392
Francisco, C.C., Gerardo, S.O., Noé, O. (2018)
The Indistinguishable Gluten Vehicle and Placebo in the Diagnosis of NCGS. Am J Gastroenterol. 2018 Jun 12. doi: 10.1038/s41395-018-0127-3. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/m/pubmed/29895979/
Friesen, P., Blease, C. (2018)
Placebo effects and racial and ethnic health disparities: an unjust and underexplored connection. J Med Ethics. doi:10.1136/medethics-2018-104811
https://www.ncbi.nlm.nih.gov/pubmed/29936435
Kong, J., Wang, Z., Leiser, J., Minicucci, D., Edwards, R., Kirsch, I., Wasan, A.D., Lang, C., Gerber, J., Yu, S., Napadow, V., Kaptchuk, T.J., Gollub, R.L. (2018)
Enhancing treatment of osteoarthritis knee pain by boosting expectancy: A functional neuroimaging study. Neuroimage Clin.18:325-334.
https://www.sciencedirect.com/science/article/pii/S2213158218300214
Lansberg, P., Lee, A., Lee, Z.V., Subramaniam, K., Setia, S. (2018)
Nonadherence to statins: individualized intervention strategies outside the pill box. Vasc Health Risk Manag. 2018 May 24;14:91-102. doi: 10.2147/VHRM.S158641. eCollection 2018. Review.
https://www.ncbi.nlm.nih.gov/pubmed/29872306
Lansdorp, C.A., van Hulst, R.A. (2018)
Double-blind trials in hyperbaric medicine: A narrative review on past experiences and considerations in designing sham hyperbaric treatment. Clin Trials. 2018 Jun 1:1740774518776952. doi: 10.1177/1740774518776952. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/29865904
Lee, I.S., Kullmann, S., Scheffler, K., Preissl, H., Enck, P. (2018)
Fat label compared with fat content: gastrointestinal symptoms and brain activity in functional dyspepsia patients and healthy controls. Am J Clin Nutr. 2018 Jun 18. doi: 10.1093/ajcn/nqy077. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/29924294
Lee, N., Kildea, S., Stapleton, H. (2018)
‘Tough love’: The experiences of midwives giving women sterile water injections for the relief of back pain in labour. Midwifery. 2017 Oct;53:80-86. doi: 10.1016/j.midw.2017.07.016. Epub 2017 Jul 22.
https://www.ncbi.nlm.nih.gov/pubmed/28779643
Liodden, I., Pripp, A.H., Norheim, A.J. (2018)
Placebo by proxy expectations toward acupuncture change over time: a survey comparing parental expectations to acupuncture pre- and postoperatively. BMC Complement Altern Med. 2018 Jun 14;18(1):183. doi: 10.1186/s12906-018-2248-z.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001019/
Lopez, F.L., Mistry, P., Batchelor, H.K., Bennett, J., Coupe, A., Ernest, T.B., Orlu, M., Tuleu, C. (2018)
Acceptability of placebo multiparticulate formulations in children and adults. Sci Rep. 2018 Jun 15;8(1):9210. doi: 10.1038/s41598-018-27446-6.
https://www.nature.com/articles/s41598-018-27446-6
Lund, K., Demant, D.T., Vase, L., Sindrup, S.H., Jensen, T.S., Finnerup, N.B. (2018)
Placebo responses in patients with peripheral neuropathic pain. Scand J Pain. 2017 Dec 29;5(3):210. doi: 10.1016/j.sjpain.2014.05.019.
https://www.ncbi.nlm.nih.gov/pubmed/29913698
Ma, C., van Rhijn, B.D., Jairath, V., Nguyen, T.M., Parker, C.E., Aceves, S.S., Furuta GT, Gupta SK, Katzka DA, Safroneeva E, Schoepfer AM, Straumann A, Spergel JM, Pai RK, Feagan BG, Hirano I, Dellon ES, Bredenoord AJ. (2018)
Heterogeneity in Clinical, Endoscopic, and Histologic Outcome Measures and Placebo Response Rates in Clinical Trials of Eosinophilic Esophagitis: A Systematic Review. Clin Gastroenterol Hepatol. 2018 Jun 13. pii: S1542-3565(18)30610-4. doi: 10.1016/j.cgh.2018.06.005. [Epub ahead of print] Review.
https://www.ncbi.nlm.nih.gov/pubmed/29908360
Maria Grillo, C., Rasera Zotelli, V.L., Lúcia Bressiani Gil, M., Luz Rosário de Sousa, M.D. (2018)
Would a placebo acupuncture needle be able to induce Deqi? J Acupunct Meridian Stud. 2018 Jun 23. pii: S2005-2901(18)30073-6. doi: 10.1016/j.jams.2018.06.007. [Epub ahead of print] No abstract available.
https://www.ncbi.nlm.nih.gov/pubmed/29944925
Matsusaki, A., Kaneko, M., Narukawa, M. (2018)
Meta-analysis of Placebo Response in Randomized Clinical Trials of Antipsychotic Drugs Using PANSS Focusing on Different Approaches to the Handling of Missing Data. Clin Drug Investig. 2018 Jun 1. doi: 10.1007/s40261-018-0661-1. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/29858840
Guo, W., Nie, L., Wang, X.R., Xu, M.L., Yang, W.J., Gao, X.Y., Cai, X.L., Ji, L.N. (2018)
Comparison of Placebo Effect between Asian and Caucasian Type 2 Diabetic Patients: A Meta-Analysis. Chin Med J (Engl). 2018 Jul 5;131(13):1605-1612. doi: 10.4103/0366-6999.235107.
https://www.ncbi.nlm.nih.gov/pubmed/29941715
Pineles D, Malter L, Liang PS, Arsuaga A, Bosworth B, Hudesman DP, Chang S. (2018)
The nocebo effect and patient perceptions of biosimilars in inflammatory bowel disease. Eur J Clin Pharmacol. 2018 May 31. doi: 10.1007/s00228-018-2492-7. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/29855655
Prado, J.M.D., Kurebayashi, L.F.S., Silva, M.J.P.D. (2018)
Experimental and placebo auriculotherapy for stressed nurses: randomized controlled trial. Rev Esc Enferm USP. 2018 Jun 11;52:e03334. doi: 10.1590/S1980-20X2017030403334.
https://www.ncbi.nlm.nih.gov/m/pubmed/29898171/
Rezk, M.F., Pieper, B. (2018)
To See or NOsee: The Debate on the Nocebo Effect and Optimizing the Use of Biosimilars. Adv Ther. 2018 Jun 5. doi: 10.1007/s12325-018-0719-8. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/29873005
Rheker, J., Rief, W., Doering, B.K., Winkler, A. (2018)
Assessment of adverse events in clinical drug trials: Identifying amitriptyline’s placebo- and baseline-controlled side effects. Exp Clin Psychopharmacol. 2018 Jun;26(3):320-326. doi: 10.1037/pha0000194.
https://www.ncbi.nlm.nih.gov/pubmed/29863388
Salanti, G., Chaimani, A., Furukawa, T.A., Higgins, J.P.T., Ogawa, Y., Cipriani, A., Egger, M. (2018)
Impact of placebo arms on outcomes in antidepressant trials: systematic review and meta-regression analysis. Int J Epidemiol. 2018 Jun 6. doi: 10.1093/ije/dyy076. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/29878123
Schumann, D., Cramer, H. (2018)
Letter: all or nothing-placebo effects in a non-drug clinical trial in IBS. Authors’ reply. Aliment Pharmacol Ther. 2018 Jul;48(1):106-107. doi: 10.1111/apt.14686.
https://www.ncbi.nlm.nih.gov/pubmed/29882979
Sigaard, J., Dinesen, B. (2018)
Are we using Placebo effects in specialized Palliative Care? Scand J Pain. 2017 Dec 29;16(1):183. doi: 10.1016/j.sjpain.2017.04.053.
https://www.ncbi.nlm.nih.gov/pubmed/29865024
Tekampe, J., Peerdeman, K.J., Bartels, D.J.P., van Laarhoven, A.I.M., Evers, A.W.M. (2018)
[Placebo and nocebo effects on itch : Methodological and clinical implications]. Hautarzt. 2018 Jun 12. doi: 10.1007/s00105-018-4211-9. [Epub ahead of print] Review. German.
https://www.ncbi.nlm.nih.gov/m/pubmed/29947820/
Thanda Han, M.A., Altayar, O., Hamdeh, S., Takyar, V., Rotman, Y., Etzion, O., Lefebvre E, Safadi R, Ratziu V, Prokop LJ, Murad MH, Noureddin M. (2018)
Rates and Factors Associated With Placebo Response in Trials of Pharmacotherapies for Nonalcoholic Steatohepatitis: Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2018 Jun 15. pii: S1542-3565(18)30621-9. doi: 10.1016/j.cgh.2018.06.011. [Epub ahead of print] Review.
https://www.ncbi.nlm.nih.gov/pubmed/29913275
Verrender, A., Loughran, S.P., Dalecki, A., Freudenstein, F., Croft, R.J. (2018)
Can explicit suggestions about the harmfulness of EMF exposure exacerbate a nocebo response in healthy controls? Environ Res. 2018 Jun 21;166:409-417. doi: 10.1016/j.envres.2018.06.032. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/29936289
Yoo, D.H., Choe, J.Y., Shim, S.C., Suh, C.H. (2018)
Switching to biosimilars in the treatment of rheumatic diseases. Expert Rev Clin Immunol. 2018 Jun 18. doi: 10.1080/1744666X.2018.1490178.
https://www.ncbi.nlm.nih.gov/pubmed/29914272
Zeitler, M., Tass, P.A. (2018)
Computationally Developed Sham Stimulation Protocol for Multichannel Desynchronizing Stimulation. Front Physiol. 2018 May 8;9:512. doi: 10.3389/fphys.2018.00512. eCollection 2018.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952302/
Zeng, Y., Hu, D., Yang, W., Hayashinaka, E., Wada, Y., Watanabe, Y., Zeng, Q., Cui, Y. (2018)
A voxel-based analysis of neurobiological mechanisms in placebo analgesia in rats. Neuroimage. doi: 10.1016/j.neuroimage.2018.06.009. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/29883731
Zheng, Z., Wong, Lit Wan, D., Arendt-Nielsen, L., Yao, D.Y., Iversen, G., Xue, C.C., Wang, K. (2018)
Being Adaptive to Pain Enhances Sham Acupuncture Analgesia: A Crossover Healthy Human Study. J Acupunct Meridian Stud. 2017 Dec;10(6):385-395. doi: 10.1016/j.jams.2017.10.002.
https://www.ncbi.nlm.nih.gov/pubmed/29275794
Zunhammer, M., Gerardi, M., Bingel, U. (2018)
The effect of dopamine on conditioned placebo analgesia in healthy individuals: a double-blind randomized trial. Psychopharmacology (Berl). 2018 Jun 25. doi: 10.1007/s00213-018-4951-3. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/29943093