Today we present 57 new placebo research papers, comments and abstracts identified during September 2018. As usual, they are based on new PUBMED publication using the search terms „placebo“ and „nocebo“ and are hand-selected from more than 992 new publications during the preceding month. Previously published monthly updates can be found in our archive. Todays selection as well as all previously identified papers will also go into our placebo research library that currently contains more than 4,000 relevant papers. If you would like to get access to the full database, please register for our newsletter and provide us with your email address and affiliation.
Ajmera, V., & Loomba, R. (2018).
Refining Sample-Size Estimations Based Upon Placebo Response in Trials of Agents for Nonalcoholic Fatty Liver Disease. Clin Gastroenterol Hepatol. doi:10.1016/j.cgh.2018.08.055
https://www.ncbi.nlm.nih.gov/pubmed/30153521
Annoni, M. (2018).
The Ethics of Placebo Effects in Clinical Practice and Research. Int Rev Neurobiol, 139, 463-484. doi:10.1016/bs.irn.2018.07.031
https://www.ncbi.nlm.nih.gov/pubmed/30146058
Arbinaga, F., Fernandez-Ozcorta, E., Saenz-Lopez, P., & Carmona, J. (2018).
The psychological effects of physical exercise: A controlled study of the placebo effect. Scand J Psychol. doi:10.1111/sjop.12482
https://www.ncbi.nlm.nih.gov/pubmed/30180291
Atmaca, M., Korucu, T., Cekic, S., Kazgan, A., Keles, D. D., Tabara, M. F., Baykara, S., & Korkmaz, S. (2018).
Should patients be informed about the side effects of psychotropic drugs? According to us: Yes. Psychiatry Res, 270, 176-179. doi:10.1016/j.psychres.2018.09.042
https://www.ncbi.nlm.nih.gov/pubmed/30261406
Blasini, M., Peiris, N., Wright, T., & Colloca, L. (2018).
The Role of Patient-Practitioner Relationships in Placebo and Nocebo Phenomena. Int Rev Neurobiol, 139, 211-231. doi:10.1016/bs.irn.2018.07.033
https://www.ncbi.nlm.nih.gov/pubmed/30146048
Blease, C. R. (2018).
Psychotherapy and Placebos: Manifesto for Conceptual Clarity. Front Psychiatry, 9, 379. doi:10.3389/fpsyt.2018.00379
https://www.ncbi.nlm.nih.gov/pubmed/30177892
Bowdring, M. A., & Sayette, M. A. (2018).
Using Placebo Beverages in Group Alcohol Studies. Alcohol Clin Exp Res. doi:10.1111/acer.13895
https://www.ncbi.nlm.nih.gov/pubmed/30247751
Cash, D. K., Heisick, L. L., & Papesh, M. H. (2018).
Expectancy effects in the Autonomous Sensory Meridian Response. PeerJ, 6, e5229. doi:10.7717/peerj.5229
https://www.ncbi.nlm.nih.gov/pubmed/30155346
Chincholkar, M. (2018).
Brain imaging of analgesic and placebo responses. Comment on Br J Anaesth 2018; 120: 299-307. Br J Anaesth, 121(4), 971. doi:10.1016/j.bja.2018.05.005
https://www.ncbi.nlm.nih.gov/pubmed/30236261
Chouchou, F., Dang-Vu, T. T., Rainville, P., & Lavigne, G. (2018).
The Role of Sleep in Learning Placebo Effects. Int Rev Neurobiol, 139, 321-355. doi:10.1016/bs.irn.2018.07.013
https://www.ncbi.nlm.nih.gov/pubmed/30146053
Colagiuri, B., Sharpe, L., & Scott, A. (2018).
The blind leading the not so blind: a meta-analysis of blinding in pharmacological trials for chronic pain. J Pain. doi:10.1016/j.jpain.2018.09.002
https://www.ncbi.nlm.nih.gov/pubmed/30248448
Coleshill, M. J., Sharpe, L., Colloca, L., Zachariae, R., & Colagiuri, B. (2018).
Placebo and Active Treatment Additivity in Placebo Analgesia: Research to Date and Future Directions. Int Rev Neurobiol, 139, 407-441. doi:10.1016/bs.irn.2018.07.021
https://www.ncbi.nlm.nih.gov/pubmed/30146056
Colloca, L. (2018).
The Placebo Effect in Pain Therapies. Annu Rev Pharmacol Toxicol. doi:10.1146/annurev-pharmtox-010818-021542
https://www.ncbi.nlm.nih.gov/pubmed/30216744
Colloca, L. (2018).
Preface: Part II: The Fascinating Mechanisms and Implications of the Placebo Effect. Int Rev Neurobiol, 139, xvii-xxiii. doi:10.1016/S0074-7742(18)30087-4
https://www.ncbi.nlm.nih.gov/pubmed/30146061
Colloca, L., Corsi, N., & Fiorio, M. (2018).
The interplay of exercise, placebo and nocebo effects on experimental pain. Sci Rep, 8(1), 14758. doi:10.1038/s41598-018-32974-2
https://rdcu.be/8oKK
Crijns, T. J., Teunis, T., Chen, N. C., & Ring, D. (2018).
Psychologic Factors Do Not Affect Placebo Responses After Upper Extremity Injections: A Randomized Trial. Clin Orthop Relat Res. doi:10.1097/CORR.0000000000000425
https://www.ncbi.nlm.nih.gov/pubmed/30179953
Farzad, M. (2018).
CORR Insights(R): Psychologic Factors Do Not Affect Placebo Responses After Upper Extremity Injections: A Randomized Trial. Clin Orthop Relat Res. doi:10.1097/CORR.0000000000000448
https://www.ncbi.nlm.nih.gov/pubmed/30179940
Damien, J., Colloca, L., Bellei-Rodriguez, C. E., & Marchand, S. (2018).
Pain Modulation: From Conditioned Pain Modulation to Placebo and Nocebo Effects in Experimental and Clinical Pain. Int Rev Neurobiol, 139, 255-296. doi:10.1016/bs.irn.2018.07.024
https://www.ncbi.nlm.nih.gov/pubmed/30146050
Darnall, B. D., & Colloca, L. (2018).
Optimizing Placebo and Minimizing Nocebo to Reduce Pain, Catastrophizing, and Opioid Use: A Review of the Science and an Evidence-Informed Clinical Toolkit. Int Rev Neurobiol, 139, 129-157. doi:10.1016/bs.irn.2018.07.022
https://www.ncbi.nlm.nih.gov/pubmed/30146045
Eltiti, S., Wallace, D., Russo, R., & Fox, E. (2018).
Symptom Presentation in Idiopathic Environmental Intolerance With Attribution to Electromagnetic Fields: Evidence for a Nocebo Effect Based on Data Re-Analyzed From Two Previous Provocation Studies. Front Psychol, 9, 1563. doi:10.3389/fpsyg.2018.01563
https://www.ncbi.nlm.nih.gov/pubmed/30210397
Enck, P., Horing, B., Broelz, E., & Weimer, K. (2018).
Knowledge Gaps in Placebo Research: With Special Reference to Neurobiology. Int Rev Neurobiol, 139, 85-106. doi:10.1016/bs.irn.2018.07.018
https://www.ncbi.nlm.nih.gov/pubmed/30146060
Faasse, K., Huynh, A., Pearson, S., Geers, A. L., Helfer, S. G., & Colagiuri, B. (2018).
The Influence of Side Effect Information Framing on Nocebo Effects. Ann Behav Med. doi:10.1093/abm/kay071
https://www.ncbi.nlm.nih.gov/pubmed/30204841
Faasse, K., & Martin, L. R. (2018).
The Power of Labeling in Nocebo Effects. Int Rev Neurobiol, 139, 379-406. doi:10.1016/bs.irn.2018.07.016
https://www.ncbi.nlm.nih.gov/pubmed/30146055
Ferreira, J. J., Trenkwalder, C., & Mestre, T. A. (2018).
Placebo and nocebo responses in other movement disorders besides Parkinson’s disease: How much do we know? Mov Disord, 33(8), 1228-1235. doi:10.1002/mds.113
https://www.ncbi.nlm.nih.gov/pubmed/30230626
Finniss, D. G. (2018).
Placebo Effects: Historical and Modern Evaluation. Int Rev Neurobiol, 139, 1-27. doi:10.1016/bs.irn.2018.07.010
https://www.ncbi.nlm.nih.gov/pubmed/30146043
Fiorio, M. (2018).
Modulation of the Motor System by Placebo and Nocebo Effects. Int Rev Neurobiol, 139, 297-319. doi:10.1016/bs.irn.2018.07.012
https://www.ncbi.nlm.nih.gov/pubmed/30146052
Frew, A. J., & Pfaar, O. (2018).
Placebo effects in allergen immunotherapy: an experts’ opinion. Allergo J Int, 27(6), 162-166. doi:10.1007/s40629-018-0065-z
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132371/
Friedrich, D. R., Reichardt, J. O., & Rittner, H. L. (2018).
[Placebo Nocebo Ethics in Communicating with Patients How Anaesthesiologists Should Handle the Psychosomatic Dimension of Briefing]. Anasthesiol Intensivmed Notfallmed Schmerzther, 53(9), 592-604. doi:10.1055/s-0043-121685
https://www.ncbi.nlm.nih.gov/pubmed/30176687
Glare, P., Fridman, I., & Ashton-James, C. E. (2018).
Choose Your Words Wisely: The Impact of Message Framing on Patients’ Responses to Treatment Advice. Int Rev Neurobiol, 139, 159-190. doi:10.1016/bs.irn.2018.07.020
https://www.ncbi.nlm.nih.gov/pubmed/30146046
Haaga, R., & Schnabel, A. (2018).
[Placebo Effects in Acute Pain Therapy]. Anasthesiol Intensivmed Notfallmed Schmerzther, 53(9), 579-590. doi:10.1055/s-0043-121684
https://www.ncbi.nlm.nih.gov/pubmed/30176686
Hardman, D. I., Geraghty, A. W., Lewith, G., Lown, M., Viecelli, C., & Bishop, F. L. (2018).
From substance to process: A meta-ethnographic review of how healthcare professionals and patients understand placebos and their effects in primary care. Health (London), 1363459318800169. doi:10.1177/1363459318800169
https://www.ncbi.nlm.nih.gov/pubmed/30238795
Hashmi, J. A. (2018).
Placebo Effect: Theory, Mechanisms and Teleological Roots. Int Rev Neurobiol, 139, 233-253. doi:10.1016/bs.irn.2018.07.017
https://www.ncbi.nlm.nih.gov/pubmed/30146049
Hoskin, R., Berzuini, C., Acosta-Kane, D., El-Deredy, W., Guo, H., & Talmi, D. (2018).
Sensitivity to pain expectations: A Bayesian model of individual differences. Cognition, 182, 127-139. doi:10.1016/j.cognition.2018.08.022
https://www.ncbi.nlm.nih.gov/pubmed/30243037
Jonas, W. B., Crawford, C., Colloca, L., Kriston, L., Linde, K., Moseley, B., & Meissner, K. (2018).
Are Invasive Procedures Effective for Chronic Pain? A Systematic Review. Pain Med. doi:10.1093/pm/pny154
https://www.ncbi.nlm.nih.gov/pubmed/30204920
Kelley, J. M. (2018).
Lumping and Splitting: Toward a Taxonomy of Placebo and Related Effects. Int Rev Neurobiol, 139, 29-48. doi:10.1016/bs.irn.2018.07.011
https://www.ncbi.nlm.nih.gov/pubmed/30146051
Klinger, R., Stuhlreyer, J., Schwartz, M., Schmitz, J., & Colloca, L. (2018).
Clinical Use of Placebo Effects in Patients With Pain Disorders. Int Rev Neurobiol, 139, 107-128. doi:10.1016/bs.irn.2018.07.015
https://www.ncbi.nlm.nih.gov/pubmed/30146044
Kubo, K., Fleischhacker, W. W., Suzuki, T., Yasui-Furukori, N., Mimura, M., & Uchida, H. (2018).
Placebo effects in adult and adolescent patients with schizophrenia: combined analysis of nine RCTs. Acta Psychiatr Scand. doi:10.1111/acps.12960
https://www.ncbi.nlm.nih.gov/pubmed/30198163
Laferton, J. A. C., Vijapura, S., Baer, L., Clain, A. J., Cooper, A., Papakostas, G., Price, L. H., Carpenter, L. L., Tyrka, A. R., Fava, M, & Mischoulon, D. (2018).
Mechanisms of Perceived Treatment Assignment and Subsequent Expectancy Effects in a Double Blind Placebo Controlled RCT of Major Depression. Front Psychiatry, 9, 424. doi:10.3389/fpsyt.2018.00424
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137256/
Lasselin, J., Petrovic, P., Olsson, M. J., Paues Goranson, S., Lekander, M., Jensen, K. B., & Axelsson, J. (2018).
Sickness behavior is not all about the immune response: Possible roles of expectations and prediction errors in the worry of being sick. Brain Behav Immun. doi:10.1016/j.bbi.2018.09.008
https://www.ncbi.nlm.nih.gov/pubmed/30217536
Mathur, A., Jarrett, P., Broadbent, E., & Petrie, K. J. (2018).
Open-label Placebos for Wound Healing: A Randomized Controlled Trial. Ann Behav Med, 52(10), 902-908. doi:10.1093/abm/kax057
https://www.ncbi.nlm.nih.gov/pubmed/30212845
Meissner, K., & Linde, K. (2018).
Are Blue Pills Better Than Green? How Treatment Features Modulate Placebo Effects. Int Rev Neurobiol, 139, 357-378. doi:10.1016/bs.irn.2018.07.014
https://www.ncbi.nlm.nih.gov/pubmed/30146054
Mestre, T. A., & Ferreira, J. J. (2018).
The placebo response in Parkinson’s disease and other movement disorders. Mov Disord, 33(8), 1193-1194. doi:10.1002/mds.27476
https://www.ncbi.nlm.nih.gov/pubmed/30230628
Mestre, T. A., Shamy, M., Benedetti, F., & Lang, A. E. (2018).
Harnessing the power of placebos in movement disorders: Insights from Parkinson’s disease in clinical research and practice. Mov Disord, 33(8), 1195-1203. doi:10.1002/mds.27409
https://www.ncbi.nlm.nih.gov/pubmed/30145820
Muller, M., & Brascher, A. K. (2018).
[Placebo Responses in Chronic Pain: State of Research and Clinical Implications]. Anasthesiol Intensivmed Notfallmed Schmerzther, 53(9), 605-617. doi:10.1055/s-0043-121683
https://www.ncbi.nlm.nih.gov/pubmed/30176688
Odinet, J. S., Day, C. E., Cruz, J. L., & Heindel, G. A. (2018).
The Biosimilar Nocebo Effect? A Systematic Review of Double-Blinded Versus Open-Label Studies. J Manag Care Spec Pharm, 24(10), 952-959. doi:10.18553/jmcp.2018.24.10.952
https://www.ncbi.nlm.nih.gov/pubmed/30247100
Pires, F. O., Dos Anjos, C. A. S., Covolan, R. J. M., Fontes, E. B., Noakes, T. D., St Clair Gibson, A., Magalhães, F. H., & Ugrinowitsch, C. (2018).
Caffeine and Placebo Improved Maximal Exercise Performance Despite Unchanged Motor Cortex Activation and Greater Prefrontal Cortex Deoxygenation. Front Physiol, 9, 1144. doi:10.3389/fphys.2018.01144
https://www.ncbi.nlm.nih.gov/pubmed/30246799
Quattrone, A., Barbagallo, G., Cerasa, A., & Stoessl, A. J. (2018).
Neurobiology of placebo effect in Parkinson’s disease: What we have learned and where we are going. Mov Disord, 33(8), 1213-1227. doi:10.1002/mds.27438
https://www.ncbi.nlm.nih.gov/pubmed/30230624
Quidde, J., Pan, Y., Salm, M., Hendi, A., Nilsson, S., Oechsle, K., Stein, A., & Nestoriuc, Y. (2018).
Preventing adverse events of chemotherapy by educating patients about the nocebo effect (RENNO study) – study protocol of a randomized controlled trial with gastrointestinal cancer patients. BMC Cancer, 18(1), 916. doi:10.1186/s12885-018-4814-7
https://www.ncbi.nlm.nih.gov/pubmed/30249191
Rato, M. L., Duarte, G. S., Mestre, T., de Carvalho, M., & Ferreira, J. J. (2018).
Strong nocebo effect in amyotrophic lateral sclerosis trials might mask conclusions. Lancet Neurol, 17(10), 842. doi:10.1016/S1474-4422(18)30310-7
https://www.ncbi.nlm.nih.gov/pubmed/30264722
Shenefelt, P. D. (2017).
Noxious nocebos in dermatology. Cutis, 100(3), 190-191.
https://www.ncbi.nlm.nih.gov/pubmed/29121131
Stoekenbroek, R. M., & Kastelein, J. J. P. (2017).
Dyslipidaemia: Statin-associated muscle symptoms – really all in the mind? Nat Rev Cardiol, 14(8), 445-446. doi:10.1038/nrcardio.2017.92
https://www.ncbi.nlm.nih.gov/pubmed/28631752
Sussex, R. (2018).
Describing Placebo Phenomena in Medicine: A Linguistic Approach. Int Rev Neurobiol, 139, 49-83. doi:10.1016/bs.irn.2018.07.032
https://www.ncbi.nlm.nih.gov/pubmed/30146059
Vachon-Presseau, E., Berger, S. E., Abdullah, T. B., Huang, L., Cecchi, G. A., Griffith, J. W., Schnitzer, T. J., & Apkarian, A. V. (2018).
Brain and psychological determinants of placebo pill response in chronic pain patients. Nat Commun, 9(1), 3397. doi:10.1038/s41467-018-05859-1
https://www.ncbi.nlm.nih.gov/pubmed/30209286
Wampold, B. E. (2018).
The Therapeutic Value of the Relationship for Placebo Effects and Other Healing Practices. Int Rev Neurobiol, 139, 191-210. doi:10.1016/bs.irn.2018.07.019
https://www.ncbi.nlm.nih.gov/pubmed/30146047
Webb, J. (2018).
Putting placebo-controlled trials in developing countries to the interpersonal justifiability test. Dev World Bioeth. doi:10.1111/dewb.12209
https://www.ncbi.nlm.nih.gov/pubmed/30226925
Webster, R. K., Weinman, J., & Rubin, G. J. (2018).
Explaining all without causing unnecessary harm: Is there scope for positively framing medical risk information? Patient Educ Couns. doi:10.1016/j.pec.2018.09.014
https://www.ncbi.nlm.nih.gov/pubmed/30243771
Zis, P., & Mitsikostas, D. D. (2018).
Nocebo Responses in Brain Diseases: A Systematic Review of the Current Literature. Int Rev Neurobiol, 139, 443-462. doi:10.1016/bs.irn.2018.07.025
https://www.ncbi.nlm.nih.gov/pubmed/30146057