Today we present 34 new placebo and nocebo research papers, comments and abstracts identified during August 2019. As usual, they are based on new PUBMED publication using the search terms „placebo“ and „nocebo“ and are hand-selected from more than 719 new publications during the preceding month. Previously published monthly updates can be found in our archive. Todays selection as well as all previously identified papers will also go into our placebo research library that currently contains more than 4,000 relevant papers. If you would like to get access to the full database, please register for our newsletter and provide us with your email address and affiliation.
Barnes, K., Yu, A., Josupeit, J., & Colagiuri, B. (2019).
Deceptive but not open label placebos attenuate motion-induced nausea. Journal of Psychosomatic Research, 125, 109808.
https://doi.org/10.1016/j.jpsychores.2019.109808
Benedetti, F. (2019).
The Dangerous Side of Placebo Research: Is Hard Science Boosting Pseudoscience? Clinical Pharmacology and Therapeutics.
https://doi.org/10.1002/cpt.1579
Benson, S., & Elsenbruch, S. (2019).
No Reason to Feel Sick? Nocebo Responses in the Placebo Arms of Experimental Endotoxemia Studies. Frontiers in Psychiatry, 10, 511.
https://doi.org/10.3389/fpsyt.2019.00511
Curkovic, M., & Borovecki, A. (2019).
The Use of Placebo in Schizophrenia Relapse Prevention Studies: Scientific or Ethical Debate? Acta Psychiatrica Scandinavica.
https://doi.org/10.1111/acps.13085
Dettori, J. R., Norvell, D. C., & Chapman, J. R. (2019).
The Art of Surgery: The Strange World of the Placebo Response. Global Spine Journal, 9(6), 680–683.
https://doi.org/10.1177/2192568219861972
Duijvestein, M., Jeyarajah, J., Guizzetti, L., Zou, G., Parker, C. E., van Viegen, T., VandeCasteele, N., Kanna, R., Van Der Aa, A., Sandborn, W. J., Feagan, B.G., D`Haens, G.R., & Jairath, V. (2019).
Response to Placebo, Measured by Endoscopic Evaluation of Crohn’s Disease Activity, in a Pooled Analysis of Data from 5 Randomized Controlled Induction Trials. Clinical Gastroenterology and Hepatology.
https://doi.org/10.1016/j.cgh.2019.08.025
Enck, P., & Klosterhalfen, S. (2019).
Placebos and the Placebo Effect in Drug Trials. Handbook of Experimental Pharmacology.
https://doi.org/10.1007/164_2019_269
Florine, B. L. (2019).
Harnessing Placebo Analgesia: Another Avenue to Opioid Reduction in Oral Surgery. Journal of Oral and Maxillofacial Surgery.
https://doi.org/10.1016/j.joms.2019.06.193
Gaab, J., Burgin, D., Locher, C., Werner, C., Urech, S., Bratschi, C., Garcia, L. B., Hauke, M., Bitter, S., Bohny, M., & Bentz, D. (2019).
Endogenous cortisol and conditioned placebo effects on pain – A randomized trial. Journal of Psychosomatic Research, 123, 109739.
https://doi.org/10.1016/j.jpsychores.2019.109739
Gomeni, R., Rabinowitz, J., Goyal, N., Bressolle-Gomeni, F. M. M., & Fava, M. (2019).
Model-Informed Approach to Assess the Treatment Effect Conditional to the Level of Placebo Response. Clinical Pharmacology and Therapeutics.
https://doi.org/10.1002/cpt.1584
Hadamitzky, M., Luckemann, L., Pacheco-Lopez, G., & Schedlowski, M. (2019).
Pavlovian conditioning of immunological and neuroendocrine functions. Physiological Reviews.
https://doi.org/10.1152/physrev.00033.2018
Hurst, P., Schipof-Godart, L., Szabo, A., Raglin, J., Hettinga, F., Roelands, B., Lane, A., Foad, A., Coleman, D., & Beedie, C. (2019).
The Placebo and Nocebo effect on sports performance: A systematic review. European Journal of Sport Science, 1–14.
https://doi.org/10.1080/17461391.2019.1655098
Krimmel, S. R., Zanos, P., Georgiou, P., Colloca, L., & Gould, T. D. (2019).
Classical conditioning of antidepressant placebo effects in mice. Psychopharmacology.
https://doi.org/10.1007/s00213-019-05347-4
Lindheimer, J. B., Stegner, A. J., Ellingson-Sayen, L. D., Van Riper, S. M., Dougherty, R. J., Falvo, M. J., & Cook, D. B. (2019).
Influence of pain anticipation on brain activity and pain perception in Gulf War Veterans with chronic musculoskeletal pain. Psychophysiology, e13452.
https://doi.org/10.1111/psyp.13452
Locher, C., Koechlin, H., Gaab, J., & Gerger, H. (2019).
The Other Side of the Coin: Nocebo Effects and Psychotherapy. Frontiers in Psychiatry, 10, 555.
https://doi.org/10.3389/fpsyt.2019.00555
Musial, F., & Enck, P. (2019).
How Dangerous Is Your Mind: Are There Health-Related Risks of Placebo/Nocebo Responses? Complementary Medicine Research, 26(4), 221–222.
https://doi.org/10.1159/000501978
Olliges, E., Schneider, S., Schmidt, G., Sinnecker, D., Muller, A., Burgdorf, C., Braun, S., Holdenrieder, S., Ebell, H., Ladwig, K. H., Meissner, K., & Ronel, J. (2019).
Placebo and Nocebo Effects in Patients With Takotsubo Cardiomyopathy and Heart-Healthy Controls. Frontiers in Psychiatry, 10, 549.
https://doi.org/10.3389/fpsyt.2019.00549
Pan, Y., Kinitz, T., Stapic, M., & Nestoriuc, Y. (2019).
Minimizing Drug Adverse Events by Informing About the Nocebo Effect-An Experimental Study. Frontiers in Psychiatry, 10, 504.
https://doi.org/10.3389/fpsyt.2019.00504
Pan, Y., Meister, R., Lowe, B., Winkelmann, A., Kaptchuk, T. J., Buhling, K. J., & Nestoriuc, Y. (2019).
Non-concealed placebo treatment for menopausal hot flushes: Study protocol of a randomized-controlled trial. Trials, 20(1), 508.
https://doi.org/10.1186/s13063-019-3575-1
Panayotov, V. S. (2019).
Studying a Possible Placebo Effect of an Imaginary Low-Calorie Diet. Frontiers in Psychiatry, 10, 550.
https://doi.org/10.3389/fpsyt.2019.00550
Polich, G., Iaccarino, M. A., Kaptchuk, T. J., Morales-Quezada, L., & Zafonte, R. (2019).
Nocebo Effects in Concussion: Is All That is Told Beneficial? American Journal of Physical Medicine & Rehabilitation.
https://doi.org/10.1097/PHM.0000000000001290
Potthoff, J., Jurinec, N., & Schienle, A. (2019).
Placebo Effects on Visual Food Cue Reactivity: An Eye-Tracking Investigation. Frontiers in Psychiatry, 10, 525.
https://doi.org/10.3389/fpsyt.2019.00525
Priebe, S., Conneely, M., McCabe, R., & Bird, V. (2019).
What can clinicians do to improve outcomes across psychiatric treatments: a conceptual review of non-specific components. Epidemiology and Psychiatric Sciences, 1–8.
https://doi.org/10.1017/S2045796019000428
Ree, A., Nilsen, K. B., Knardahl, S., Sand, T., & Matre, D. (2019).
Sleep restriction does not potentiate nocebo-induced changes in pain and cortical potentials. European Journal of Pain.
https://doi.org/10.1002/ejp.1466
Schruers, K., Baldi, S., van den Heuvel, T., Goossens, L., Luyten, L., Leentjens, A. F. G., Ackermans, L., Temel, Y., & Viechtbauer, W. (2019).
The effects of deep-brain non-stimulation in severe obsessive-compulsive disorder: an individual patient data meta-analysis. Translational Psychiatry, 9(1), 183.
https://doi.org/10.1038/s41398-019-0522-6
Skyt, I., Lunde, S. J., Baastrup, C., Svensson, P., Jensen, T. S., & Vase, L. (2019).
Neurotransmitter systems involved in placebo and nocebo effects in healthy participants and patients with chronic pain: a systematic review. Pain.
https://doi.org/10.1097/j.pain.0000000000001682
Spanou, I., Mavridis, T., & Mitsikostas, D. D. (2019).
Nocebo in Biosimilars and Generics in Neurology: A Systematic Review. Frontiers in Pharmacology.
https://doi.org/10.3389/fphar.2019.00809
Swafford, A. P., Kwon, D. P., MacLennan, R. J., Fukuda, D. H., Stout, J. R., & Stock, M. S. (2019).
No acute effects of placebo or open-label placebo treatments on strength, voluntary activation, and neuromuscular fatigue. European Journal of Applied Physiology.
https://doi.org/10.1007/s00421-019-04219-1
Takakura, N., Takayama, M., Nishiwaki, M., & Yajima, H. (2018).
Blinding indices and blinding scenarios of practitioners and patients with acupuncture needles for double blinding. Acupuncture in Medicine, 36 (2), 123-124.
https://doi.org/10.1136/acupmed-2017-011430
Tetreault, P. (2019).
Can Functional Brain Connectivity Predict Placebo Response in Chronic Pain? Clinical Pharmacology and Therapeutics.
https://doi.org/10.1002/cpt.1581
van Vliet, L. M., Francke, A. L., Meijers, M. C., Westendorp, J., Hoffstadt, H., Evers, A. W. M., van der Wall, E., de Jong, P., Peerdeman, K. J., Stouthard, J., & van Dulmen, S. (2019).
The Use of Expectancy and Empathy When Communicating With Patients With Advanced Breast Cancer; an Observational Study of Clinician-Patient Consultations. Frontiers in Psychiatry, 10, 464.
https://doi.org/10.3389/fpsyt.2019.00464
Vase, L. (2019).
Can Insights From Placebo and Nocebo Mechanism Studies Help Improve Randomized Controlled Trials? Clinical Pharmacology and Therapeutics.
https://doi.org/10.1002/cpt.1580
Vögtle, E., Kröner-Herwig, B., & Barke, A. (2019).
Nocebo Hyperalgesia can be Induced by the Observation of a Model Showing Natural Pain Expressions. The Clinical Journal of Pain, 35(9), 737–743.
https://doi.org/10.1097/AJP.0000000000000734
Yin, X.-S., Yang, J.-Y., Cao, S., & Wang, Y. (2019).
Failure of Placebo Analgesia Model in Rats with Inflammatory Pain. Neuroscience Bulletin.
https://doi.org/10.1007/s12264-019-00420-6