Today we present 36 new placebo and nocebo research papers, comments and abstracts identified during November 2020. As usual, they are based on new PUBMED publication using the search terms „placebo“ and „nocebo“ and are hand-selected from more than 1038 new publications during the preceding month. Previously published monthly updates can be found in our archive. Todays selection as well as all previously identified papers will also go into our placebo research library that currently contains more than 4,500 relevant papers. If you would like to get access to the full database, please register for our newsletter and provide us with your email address and affiliation.
Agnihotri, K. (2020).
The nocebo effect in current practice. Can Fam Physician, 66(11), 862-864.
https://www.ncbi.nlm.nih.gov/pubmed/33208431
Amanzio, M., Howick, J., Bartoli, M., Cipriani, G. E., & Kong, J. (2020).
How Do Nocebo Phenomena Provide a Theoretical Framework for the COVID-19 Pandemic? Front Psychol, 11, 589884. doi:10.3389/fpsyg.2020.589884
https://www.ncbi.nlm.nih.gov/pubmed/33192929
Boehmert, C., Witthoft, M., & Van den Bergh, O. (2020).
Causal perception is central in electromagnetic hypersensitivity – a commentary on “Electromagnetic hypersensitivity: a critical review of explanatory hypotheses”. Environ Health, 19(1), 122. doi:10.1186/s12940-020-00652-4
https://www.ncbi.nlm.nih.gov/pubmed/33239049
Bourdette, D. (2020).
Are drugs for multiple sclerosis fatigue just placebos? Lancet Neurol. doi:10.1016/S1474-4422(20)30415-4
https://www.ncbi.nlm.nih.gov/pubmed/33242420
Carvalho, C., Pais, M., Cunha, L., Rebouta, P., Kaptchuk, T. J., & Kirsch, I. (2020).
Open-label placebo for chronic low back pain: a 5-year follow-up. Pain. doi: 10.1097/j.pain.0000000000002162. Advance online publication.
https://www.ncbi.nlm.nih.gov/pubmed/33259459/
Ceriani Cernadas, J. M. (2020).
The placebo effect and ethics in medical practice. Arch Argent Pediatr, 118(6), 370-371. doi:10.5546/aap.2020.eng.370
https://www.ncbi.nlm.nih.gov/pubmed/33231040
Chen, J., Liu, X., Bai, T., & Hou, X. (2020).
Impact of Clinical Outcome Measures on Placebo Response Rates in Clinical Trials for Chronic Constipation: A Systematic Review and Meta-analysis. Clin Transl Gastroenterol, 11(11), e00255.
https://www.ncbi.nlm.nih.gov/pubmed/33259160/
Cheung, C. P., Thiyagarajah, M. T., Abraha, H. Y., Liu, C. S., Lanctot, K. L., Kiss, A. J., Saleem, M., Juda, A., Levitt, A. J., Schaffer, A., Cheung, A. H., & Sinyor, M. (2020).
The association between placebo arm inclusion and adverse event rates in antidepressant randomized controlled trials: An examination of the Nocebo Effect. J Affect Disord, 280(Pt A), 140-147. doi:10.1016/j.jad.2020.11.004
https://www.ncbi.nlm.nih.gov/pubmed/33212405
Choi, J. H., Shin, C., Kim, H. J., & Jeon, B. (2020).
Placebo response in degenerative cerebellar ataxias: a descriptive review of randomized, placebo-controlled trials. J Neurol. doi:10.1007/s00415-020-10306-7
https://www.ncbi.nlm.nih.gov/pubmed/33219422
Cohen, E. A., Hassman, H. H., Ereshefsky, L., Walling, D. P., Grindell, V. M., Keefe, R. S. E., Wyka, K., & Horan, W. P. (2020).
Placebo response mitigation with a participant-focused psychoeducational procedure: a randomized, single-blind, all placebo study in major depressive and psychotic disorders. Neuropsychopharmacology. doi:10.1038/s41386-020-00911-5
https://www.ncbi.nlm.nih.gov/pubmed/33244149
da Silva, J., de Azevedo, K. P. M., Farinasso, C. M., da Silva, D. L. M., Stefani, C., Figueiredo, A., de Souza, P. M., Piuvezam, G., & Capucho, H. C. (2020).
Placebo use and outcome quality: A protocol for systematic review and meta-analysis. Medicine, 99(44), e22915. doi:10.1097/MD.0000000000022915
https://www.ncbi.nlm.nih.gov/pubmed/33126350
Davies, J. N., Sharpe, L., Day, M. A., & Colagiuri, B. (2020).
Mindfulness-based analgesia or placebo effect? The development and evaluation of a sham mindfulness intervention for acute experimental pain. Psychosom Med. doi:10.1097/PSY.0000000000000886
https://www.ncbi.nlm.nih.gov/pubmed/33165219
Dieudonne, M. (2020).
Answer to Bohmert et al. Environ Health, 19(1), 126. doi:10.1186/s12940-020-00676-w
https://www.ncbi.nlm.nih.gov/pubmed/33239027
Disley, N., Kola-Palmer, S., & Retzler, C. (2020).
A comparison of open-label and deceptive placebo analgesia in a healthy sample. J Psychosom Res, 140, 110298. doi:10.1016/j.jpsychores.2020.110298
https://www.ncbi.nlm.nih.gov/pubmed/33227553
Enck, P., & Klosterhalfen, S. (2020).
Placebo Responses and Placebo Effects in Functional Gastrointestinal Disorders. Front Psychiatry, 11, 797. doi:10.3389/fpsyt.2020.00797
https://www.ncbi.nlm.nih.gov/pubmed/33192627
Fox, K. C. R., & Parvizi, J. (2020).
Fidelity of first-person reports following intracranial neuromodulation of the human brain: An empirical assessment of sham stimulation in neurosurgical patients. Brain Stimul, 14(1), 77-79. doi:10.1016/j.brs.2020.10.015
https://www.ncbi.nlm.nih.gov/pubmed/33130019
Fragoulis, G. E., Evangelatos, G., Arida, A., Bournia, V. K., Fragiadaki, K., Karamanakos, A., Kravvariti, E., Laskari, K., Panopoulos, S., Pappa, M., Mitsikostas, D. D., Tektonidou, M. G., & Sfikakis, P. P. (2020).
Nocebo-Prone Behaviour in Patients with Autoimmune Rheumatic Diseases during the COVID-19 Pandemic. Mediterr J Rheumatol, 31(Suppl 2), 288-294. doi:10.31138/mjr.31.3.288
https://www.ncbi.nlm.nih.gov/pubmed/33196007
Furlan, G., & Power, D. (2020).
The Unintended Consequences of Adverse Event Information on Medicines’ Risks and Label Content. Pharmaceut Med. doi:10.1007/s40290-020-00367-4
https://www.ncbi.nlm.nih.gov/pubmed/33196966
Ghanizada, H., Iljazi, A., Ashina, H., Do, T. P., Al-Karagholi, M. A., Amin, F. M., & Ashina, M. (2020).
Nocebo response in human models of migraine: A systematic review and meta-analysis of randomized, double-blind, placebo-controlled, two-way crossover trials in migraine without aura and healthy volunteers. Cephalalgia. doi:10.1177/0333102420970489
https://www.ncbi.nlm.nih.gov/pubmed/33241720
Goncalves, M., Matos, L. C., Duarte, L., Machado, J., Greten, H. J., & Franconi, G. (2020).
Problems of scientific methodology related to placebo control in Qigong studies: A systematic review. J Bodyw Mov Ther, 24(4), 261-270. doi:10.1016/j.jbmt.2020.06.035
https://www.ncbi.nlm.nih.gov/pubmed/33218521
Harper, T. E., Christensen, R. D., & Rothstein, G. (1987).
The effect of administration of immunoglobulin to newborn rats with Escherichia coli sepsis and meningitis. Pediatr Res, 22(4), 455-460. doi:10.1203/00006450-198710000-00019
https://www.ncbi.nlm.nih.gov/pubmed/3317257
Harris, I. A., Poolman, R. W., & Buchbinder, R. (2020).
Placebo Trials in Orthopaedic Surgery. Arthroscopy, 36(11), 2777–2778. doi: 10.1016/j.arthro.2020.08.015.
https://www.ncbi.nlm.nih.gov/pubmed/33172573
Horing, B., Beadle, S. C., Inks, Z., Robb, A., Muth, E. R., & Babu, S. V. (2020).
A virtual experimenter does not increase placebo hypoalgesia when delivering an interactive expectancy manipulation. Sci Rep, 10(1), 20353. doi:10.1038/s41598-020-77453-9
https://www.ncbi.nlm.nih.gov/pubmed/33230290
Isawa, M., Kajiyama, M., Tominaga, K., Nakada, H., Aomori, T., & Mochizuki, M. (2020).
Review of clinical studies on the nocebo effect. Pharmazie, 75(11), 548-553. doi:10.1691/ph.2020.0642
https://www.ncbi.nlm.nih.gov/pubmed/33239127
Lin, C., Cai, X., Yang, W., Lv, F., Nie, L., & Ji, L. (2020).
Age, sex, disease severity, and disease duration difference in placebo response: implications from a meta-analysis of diabetes mellitus. BMC Med, 18(1), 322. doi:10.1186/s12916-020-01787-4
https://www.ncbi.nlm.nih.gov/pubmed/33190640
Moon, J., Cohen Sedgh, R., & Jackevicius, C. (2020).
Examining the Nocebo Effect of Statins Through Statin Adverse Events Reported in the FDA Adverse Event Reporting System (FAERS). Circ Cardiovasc Qual Outcomes. doi:10.1161/CIRCOUTCOMES.120.007480
https://www.ncbi.nlm.nih.gov/pubmed/33161769
Mostafaei, H., Mori, K., Quhal, F., Miura, N., Motlagh, R. S., Pradere, B., Laukhtina, E., Lysenko, I., Ghaffari, S., Hajebrahimi, S., & Shariat, S. F. (2020).
Nocebo Response in the Pharmacological Management of Overactive Bladder: A Systematic Review and Meta-analysis. Eur Urol Focus. doi:10.1016/j.euf.2020.10.010
https://www.ncbi.nlm.nih.gov/pubmed/33153953
Moussa, R. (2020).
Educating Medical Students Regarding the Use of Placebo in Clinical Practice and Research [Letter]. Adv Med Educ Pract, 11, 799-800. doi:10.2147/AMEP.S285645
https://www.ncbi.nlm.nih.gov/pubmed/33149718
Pan, Y., Meister, R., Lowe, B., Kaptchuk, T. J., Buhling, K. J., & Nestoriuc, Y. (2020).
Open-label placebos for menopausal hot flushes: a randomized controlled trial. Sci Rep, 10(1), 20090. doi:10.1038/s41598-020-77255-z
https://www.ncbi.nlm.nih.gov/pubmed/33208855
Rossettini, G., Geri, T., Palese, A., Marzaro, C., Mirandola, M., Colloca, L., Fiorio, M., Turolla, A., Manoni, M., & Testa, M. (2020).
What Physiotherapists Specialized in Orthopedic Manual Therapy Know About Nocebo-Related Effects and Contextual Factors: Findings From a National Survey. Front Psychol, 11, 582174. doi:10.3389/fpsyg.2020.582174
https://www.ncbi.nlm.nih.gov/pubmed/33192904
Schlintl, C., & Schienle, A. (2020).
Effects of Coloring Food Images on the Propensity to Eat: A Placebo Approach With Color Suggestions. Front Psychol, 11, 589826. doi:10.3389/fpsyg.2020.589826
https://www.ncbi.nlm.nih.gov/pubmed/33192928
Shi, Y., Huang, S., Zhan, H., Wang, Y., Zeng, Y., Cai, G., Yang, J., & Wu, W. (2020).
Personality Differences of Brain Networks in Placebo Analgesia and Nocebo Hyperalgesia: A Psychophysiological Interaction (PPI) Approach in fMRI. Neural Plast, 2020, 8820443. doi:10.1155/2020/8820443
https://www.ncbi.nlm.nih.gov/pubmed/33133178
Sochacki, K. R., Dong, D., Harris, J. D., Mather, R. C., Nwachukwu, B. U., Nho, S. J., & Cote, M. P. (2020).
Author Reply to “Placebo Trials in Orthopaedic Surgery” and “Review of Randomized Placebo-Controlled Trials”. Arthroscopy, 36(11), 2779-2784. doi:10.1016/j.arthro.2020.08.017
https://www.ncbi.nlm.nih.gov/pubmed/33172575
Speich, B., Logullo, P., Deuster, S., Marian, I. R., Moschandreas, J., Heravi, A. T., Gloy, V., Briel, M., & Hopewell, S., Making Randomized Trials Affordable Group (2020).
A meta-research study revealed several challenges in obtaining placebos for investigator-initiated drug trials. J Clin Epidemiol. doi:10.1016/j.jclinepi.2020.11.007
https://www.ncbi.nlm.nih.gov/pubmed/33242608
Tselios, K., Wakani, L., Gladman, D. D., Su, J., & Urowitz, M. B. (2020).
Response to placebo in non-renal, non-neuropsychiatric systemic lupus erythematosus: a systematic review and pooled analysis. Rheumatology. doi:10.1093/rheumatology/keaa655
https://www.ncbi.nlm.nih.gov/pubmed/33140092
Yeung, V. W., & Geers, A. L. (2020).
Prior Pain Exposure and Mere Possession of a Placebo Analgesic Predict Placebo Analgesia: Findings From a Randomized, Double-Blinded, Controlled Trial. J Pain. doi:10.1016/j.jpain.2020.10.004
https://www.ncbi.nlm.nih.gov/pubmed/33127585