Today we present 19 new placebo and nocebo research papers, book chapters, comments and abstracts identified during December 2022. As usual, they are based on new PUBMED publication using the search terms „placebo“ and „nocebo“ and are hand-selected from more than 796 new publications during the preceding month. Previously published monthly updates can be found in our archive. Todays selection as well as all previously identified papers will also go into our placebo research library that currently contains nearly 5,000 relevant papers. If you would like to get access to the full database, please register for our newsletter and provide us with your email address and affiliation.
Afach, S., Le Cleach, L., & Sbidian, E. (2022).
Placebo response in moderate-to-severe psoriasis: prevalence meta-analysis of randomised controlled trials. J Invest Dermatol. doi:10.1016/j.jid.2022.10.024
https://www.ncbi.nlm.nih.gov/pubmed/36563778
Bavbek, S., Ozyigit, L. P., Baiardini, I., Braido, F., Roizen, G., & Jerchow, E. (2022).
Placebo, Nocebo and Patient Reported Outcome Measures in Drug Allergy. J Allergy Clin Immunol Pract. doi:10.1016/j.jaip.2022.11.033
https://www.ncbi.nlm.nih.gov/pubmed/36521832
Bender, F. L., Rief, W., & Wilhelm, M. (2023).
Really just a little prick? A meta-analysis on adverse events in placebo control groups of seasonal influenza vaccination RCTs. Vaccine, 41(2), 294-303. doi:10.1016/j.vaccine.2022.11.033
https://www.ncbi.nlm.nih.gov/pubmed/36464541
Branco, P., Berger, S., Abdullah, T., Vachon-Presseau, E., Cecchi, G., & Apkarian, A. V. (2022).
Predicting placebo analgesia in patients with chronic pain using natural language processing: a preliminary validation study. Pain. doi:10.1097/j.pain.0000000000002808
https://www.ncbi.nlm.nih.gov/pubmed/36524810
Clayton, A. (2022).
Correction to: Gender-Affirming Treatment of Gender Dysphoria in Youth: A Perfect Storm Environment for the Placebo Effect-The Implications for Research and Clinical Practice. Arch Sex Behav. doi:10.1007/s10508-022-02501-6
https://www.ncbi.nlm.nih.gov/pubmed/36512169
de Bruijn, C. M. A., Hamming, G. A. C., Knibbe, C. A. J., Tromp, E., Benninga, M. A., & Vlieger, A. M. (2022).
Teenagers’ and parental individual needs for side effects information and the influence of nocebo effect education. Patient Educ Couns, 108, 107587. doi:10.1016/j.pec.2022.107587
https://www.ncbi.nlm.nih.gov/pubmed/36516654
Forkmann, K., Mussgens, D., Hashim, A., & Bingel, U. (2022).
Worth a try – A survey on the general acceptance of open-label placebos. J Psychosom Res, 111096. doi:10.1016/j.jpsychores.2022.111096
https://www.ncbi.nlm.nih.gov/pubmed/36473733Gaab, J. (2022). The reasons for its effectiveness, however, remain in dispute—A tribute to Irving Kirsch. Frontiers in Psychology, 13. doi:10.3389/fpsyg.2022.1037678 https://www.frontiersin.org/articles/10.3389/fpsyg.2022.1037678
Glissen Brown, J. R., Sanayei, A., Proctor, S., Flanagan, R., Ballou, S., Bain, P. A., & Nee, J. (2023).
Examining the Nocebo Effect in Trials of Neuromodulators for Use in Disorders of Gut-Brain Interaction. Am J Gastroenterol. doi:10.14309/ajg.0000000000002108
https://www.ncbi.nlm.nih.gov/pubmed/36563308
Hoffman, Y. S. G., Levin, Y., Palgi, Y., Goodwin, R., Ben-Ezra, M., & Greenblatt-Kimron, L. (2022).
Vaccine hesitancy prospectively predicts nocebo side-effects following COVID-19 vaccination. Sci Rep, 12(1), 20018. doi:10.1038/s41598-022-21434-7
https://www.ncbi.nlm.nih.gov/pubmed/36470896
Khemiss, M., Chaabouni, D., Ben Khaled, R., & Ben Khelifa, M. (2022).
Place of placebo therapy in the treatment of burning mouth syndrome: A systematic review. Dent Med Probl, 59(4), 603-616. doi:10.17219/dmp/152646
https://www.ncbi.nlm.nih.gov/pubmed/36548518
Kim, T. H., Lee, M. S., & Lee, H. (2022).
Sham Acupuncture Is Not Just a Placebo. J Acupunct Meridian Stud, 15(6), 333-335. doi:10.51507/j.jams.2022.15.6.333
https://www.ncbi.nlm.nih.gov/pubmed/36537115
Labarca, G., Montenegro, R., Oscullo, G., Henriquez-Beltran, M., Uribe, J. P., Gomez-Olivas, J. D., Garcia-Ortega, Alberto & Martinez-Garcia, M. A. (2022).
Placebo response in objective and subjective measures of hypersomnia in randomized clinical trials on obstructive sleep apnea. A systematic review and meta-analysis. Sleep Med Rev, 67, 101720. doi:10.1016/j.smrv.2022.101720
https://www.ncbi.nlm.nih.gov/pubmed/36495752
Pitron, V., Haanes, J. V., Hillert, L., Koteles, F. G., Leger, D., Lemogne, C., Nordin, S., Szemerszky, R., van Kamp, I., van Thriel, C., Witthoft, M. & Van den Bergh, O. (2022).
Electrohypersensitivity is always real. Environ Res, 218, 114840. doi:10.1016/j.envres.2022.114840
https://www.ncbi.nlm.nih.gov/pubmed/36463993
Romanella, S. M., Mencarelli, L., Burke, M. J., Rossi, S., Kaptchuk, T. J., & Santarnecchi, E. (2022).
Targeting neural correlates of placebo effects. Cogn Affect Behav Neurosci. doi:10.3758/s13415-022-01039-3
https://www.ncbi.nlm.nih.gov/pubmed/36517733
Sezer, D., Locher, C., & Gaab, J. (2022).
Deceptive and open-label placebo effects in experimentally induced guilt: a randomized controlled trial in healthy subjects. Sci Rep, 12(1), 21219. doi:10.1038/s41598-022-25446-1
https://www.ncbi.nlm.nih.gov/pubmed/36481801
Tu, Y., Zhang, L., & Kong, J. (2022).
Placebo and nocebo effects: from observation to harnessing and clinical application. Transl Psychiatry, 12(1), 524. doi:10.1038/s41398-022-02293-2
https://www.ncbi.nlm.nih.gov/pubmed/36564374
Wartolowska, K. A., Hohenschurz-Schmidt, D., Vase, L., & Aronson, J. K. (2022).
The importance of using placebo controls in non-pharmacological randomised trials. Pain. doi:10.1097/j.pain.0000000000002839
https://www.ncbi.nlm.nih.gov/pubmed/36472324
Zhou, T. (2023).
Estimation of placebo effect in randomized placebo-controlled trials for moderate or severe vasomotor symptoms: a meta-analysis. Menopause, 30(1), 5-10. doi:10.1097/GME.0000000000002094
https://www.ncbi.nlm.nih.gov/pubmed/36576440
Placebo in the media
Interview with Ted J. Kaptchuk on US public television: https://www.youtube.com/watch?v=eqvXiDaO3-4
Download PDF here.