Today we present 24 new placebo and nocebo research papers, book chapters, comments and abstracts identified during August 2023. As usual, they are based on new PUBMED publication using the search terms „placebo“ and „nocebo“ and are hand-selected from more than 950 new publications during the preceding month. Previously published monthly updates can be found in our archive. Todays selection as well as all previously identified papers will also go into our placebo research library that currently contains nearly 5,000 relevant papers. If you would like to get access to the full database, please register for our newsletter and provide us with your email address and affiliation.
Colloca, L. (2023).
The Nocebo Effect. Annu Rev Pharmacol Toxicol. doi:10.1146/annurev-pharmtox-022723-112425
https://www.ncbi.nlm.nih.gov/pubmed/37585661
de Salles Painelli, V., Fernandes, E., Brietzke, C., & Pires, F. O. (2023).
The placebo effect of a pink non-caloric, artificially sweetened solution on strength endurance performance and psychological responses in trained individuals. Nutr Health, 2601060231196590. doi:10.1177/02601060231196590
https://www.ncbi.nlm.nih.gov/pubmed/37608532
Falkenberg, I., Bitsch, F., Liu, W., Matsingos, A., Noor, L., Vogelbacher, C., Yildiz, C. & Kircher, T. (2023).
The effects of esketamine and treatment expectation in acute major depressive disorder (Expect): study protocol for a pharmacological fMRI study using a balanced placebo design. Trials, 24(1), 514. doi:10.1186/s13063-023-07556-x
https://www.ncbi.nlm.nih.gov/pubmed/37568215
Feng, Y., Li, R., Zhang, Q., Pei, Q., He, X., Chen, F., Wang, D., Liu, X., Liu, J., Hou, X. & Bai, T. (2023).
Nocebo Response Intensity and Influencing Factors in the Randomized Clinical Trials of Functional Dyspepsia: A Systematic Review and Meta-analysis. J Dig Dis. doi:10.1111/1751-2980.13216
https://www.ncbi.nlm.nih.gov/pubmed/37577771
Frisaldi, E., Vollert, J., Al Sultani, H., Benedetti, F., & Shaibani, A. (2023).
Placebo and nocebo responses in painful diabetic neuropathy: systematic review and meta-analysis. Pain. doi:10.1097/j.pain.0000000000003000
https://www.ncbi.nlm.nih.gov/pubmed/37530658
Frommelt, T., Traykova, M., Platt, B., & Wittekind, C. E. (2023).
The influence of outcome expectancy on interpretation bias training in social anxiety: an experimental pilot study. Pilot Feasibility Stud, 9(1), 144. doi:10.1186/s40814-023-01371-6
https://www.ncbi.nlm.nih.gov/pubmed/37592317
Gomeni, R., Bressolle-Gomeni, F., & Fava, M. (2023).
A new method for analyzing clinical trials in depression based on individual propensity to respond to placebo estimated using artificial intelligence. Psychiatry Res, 327, 115367. doi:10.1016/j.psychres.2023.115367
https://www.ncbi.nlm.nih.gov/pubmed/37544088
Gurton, W. H., Matta, G. G., Gough, L. A., Ranchordas, M. K., King, D. G., & Hurst, P. (2023). Sodium Bicarbonate and Time-to-Exhaustion Cycling Performance: A Retrospective Analysis Exploring the Mediating Role of Expectation. Sports Med Open, 9(1), 65. doi:10.1186/s40798-023-00612-5
https://www.ncbi.nlm.nih.gov/pubmed/37523028
Haikalis, N. K., Hooyman, A., Wang, P., Daliri, A., & Schaefer, S. Y. (2023).
Placebo effects of transcranial direct current stimulation on motor skill acquisition. Neurosci Lett, 814, 137442. doi:10.1016/j.neulet.2023.137442
https://www.ncbi.nlm.nih.gov/pubmed/37591359
Henrich, L., Wilhelm, M., Lange, P., & Rief, W. (2023).
The role of the communicated treatment rationale on treatment outcome: study protocol for a randomized controlled trial. Trials, 24(1), 540. doi:10.1186/s13063-023-07557-w
https://www.ncbi.nlm.nih.gov/pubmed/37592320
Liu, W., & Zhang, B. (2023).
Joint evaluation of placebo and treatment effects in cluster randomized trials by causal inference models. Contemp Clin Trials, 132, 107308. doi:10.1016/j.cct.2023.107308
https://www.ncbi.nlm.nih.gov/pubmed/37517684
Mameli, F., Zirone, E., Girlando, R., Scagliotti, E., Rigamonti, G., Aiello, E. N., Poletti, B., Ferrucci, R., Ticozzi, N., Silani, V., Locatelli, M., Barbieri, S. & Ruggiero, F. (2023).
Role of expectations in clinical outcomes after deep brain stimulation in patients with Parkinson’s disease: a systematic review. J Neurol. doi:10.1007/s00415-023-11898-6
https://www.ncbi.nlm.nih.gov/pubmed/37517038
Regnier, S. A., & Lee, X. Y. (2023).
Meta-regression to explain the placebo effects in clinical trials of anti-CGRP monoclonal antibodies for migraine prevention. J Med Econ, 26(1), 1072-1080. doi:10.1080/13696998.2023.2248842
https://www.ncbi.nlm.nih.gov/pubmed/37594778
Rhodes, J. R., Alldredge, C. T., & Elkins, G. R. (2023).
Magnitude of placebo response in clinical trials of paroxetine for vasomotor symptoms: a meta-analysis. Front Psychiatry, 14, 1204163. doi:10.3389/fpsyt.2023.1204163
https://www.ncbi.nlm.nih.gov/pubmed/37599891
Roy, S., Dietrich, K. N., Gomez, H. F., & Edwards, M. A. (2023).
Considering Some Negative Implications of an Ever-Decreasing U.S. Centers for Disease Control and Prevention (CDC) Blood Lead Threshold and “No Safe Level” Health Messaging. Environ Sci Technol, 57(35), 12935-12939. doi:10.1021/acs.est.3c04766
https://www.ncbi.nlm.nih.gov/pubmed/37611243
Sampath Kumar, S., Bano, S., & Jagan, P. (2023).
Placebo hypoalgesic and nocebo hyperalgesic effects in post-extraction patients-A cross sectional study. Br J Pain, 17(4), 366-374. doi:10.1177/20494637231161915
https://www.ncbi.nlm.nih.gov/pubmed/37538946
Schienle, A., Kogler, W., & Wabnegger, A. (2023).
A randomized trial that compared brain activity, efficacy and plausibility of open-label placebo treatment and cognitive repappraisal for reducing emotional distress. Sci Rep, 13(1), 13998. doi:10.1038/s41598-023-39806-y
https://www.ncbi.nlm.nih.gov/pubmed/37634020
Spinella, T. C., Burdeyny, V., Oprea, A., Perrot, T. S., & Barrett, S. P. (2023).
The Impact of Cannabidiol Expectancy on Cortisol Responsivity in the Context of Acute Stress: Associations with Biological Sex. Cannabis Cannabinoid Res. doi:10.1089/can.2022.0326
https://www.ncbi.nlm.nih.gov/pubmed/37552817
Sun, C. Y., Xiong, Z. Y., Sun, C. Y., Ma, P. H., Liu, X. Y., Sun, C. Y., Xin, Z. Y., Liu, B. Y., Liu, C. Z. & Yan, S. Y. (2023).
Placebo response of sham acupuncture in patients with primary dysmenorrhea: A meta-analysis. J Integr Med. doi:10.1016/j.joim.2023.08.005
https://www.ncbi.nlm.nih.gov/pubmed/37620224
Tseng, P. T., Zeng, B. S., Thompson, T., Stubbs, B., Hsueh, P. R., Su, K. P., Chen, Y. W., Chen, T. Y., Wu, Y. C., Lin, P. Y., Carvalho, A. F., Hsu, C. W., Li, D. J., Yeh, T. C., Sun, C. K., Cheng, Y. S., Shiue, Y. L., Liang, C. S. & Tu, Y. K. (2023).
Placebo effects on all-cause mortality of COVID-19 patients in randomized controlled trials of interleukin-6 antagonists: a systematic review and network meta-analysis. Psychiatry Clin Neurosci. doi:10.1111/pcn.13592
https://www.ncbi.nlm.nih.gov/pubmed/37646204
Weik, E., Neuenschwander, R., Edgington, B., Jensen, K., Tipper, C. M., & Oberlander, T. F. (2023).
Conditioning induced placebo-like and nocebo-like effects of thermal discomfort in adults but not in youth. Br J Pain, 17(4), 342-351. doi:10.1177/20494637231153364
https://www.ncbi.nlm.nih.gov/pubmed/37538948
Xiong, Z. Y., Liu, X. Y., Ma, P. H., Sun, C. Y., Sun, C. Y., Liu, T. L., Liu, B. Y., Liu, C. Z. & Yan, S. Y. (2023).
Placebo Response among Different Types of Sham Acupuncture for Low Back Pain: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Chin J Integr Med. doi:10.1007/s11655-023-3608-1
https://www.ncbi.nlm.nih.gov/pubmed/37580465
Yu, S. P., van Middelkoop, M., Deveza, L. A., Ferreira, M. L., Bierma-Zeinstra, S., Zhang, W., Atchia, I., Birrell, F., Bhagavath, V. & Hunter, D. J. (2023).
Predictors of placebo response to local (intra-articular) therapy in osteoarthritis – an individual participant data meta-analysis. Arthritis Care Res. doi:10.1002/acr.25212
https://www.ncbi.nlm.nih.gov/pubmed/37525486
Zhang, Y., Huang, W., Shan, Z., Zhou, Y., Qiu, T., Hu, L., Yang, L., Wang, Y. & Xiao, Z. (2023).
A new experimental rat model of nocebo-related nausea involving double mechanisms of observational learning and conditioning. CNS Neurosci Ther. doi:10.1111/cns.14389
https://www.ncbi.nlm.nih.gov/pubmed/37545429
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