Placebo Publications March 2022

Today we present 25 new placebo and nocebo research papers, book chapters, comments and abstracts identified during March 2022. As usual, they are based on new PUBMED publication using the search terms „placebo“ and „nocebo“ and are hand-selected from more than 860 new publications during the preceding month. Previously published monthly updates can be found in our archive. Todays selection as well as all previously identified papers will also go into our placebo research library that currently contains nearly 5,000 relevant papers. If you would like to get access to the full database, please register for our newsletter and provide us with your email address and affiliation.

Andreas, S., Rover, C., Heinz, J., Taube, C., & Friede, T. (2022).
COPD mortality and exacerbations in the placebo group of clinical trials over two decades: a systematic review and meta-regression. ERJ Open Res, 8(1). doi:10.1183/23120541.00261-2021
https://www.ncbi.nlm.nih.gov/pubmed/35265703

Arandia, I. R., & Di Paolo, E. A. (2022).
On symptom perception, placebo effects, and the Bayesian brain. Pain, 163(4), e604. doi:10.1097/j.pain.0000000000002488
https://www.ncbi.nlm.nih.gov/pubmed/35302976

Bajcar, E. A., Swedziol, W., Wrzesniewski, K., Blecharz, J., & Babel, P. (2022).
The Effects of Pain Expectancy and Desire for Pain Relief on the Memory of Pain in Half Trail Marathon Runners. J Pain Res, 15, 181-191. doi:10.2147/JPR.S336485
https://www.ncbi.nlm.nih.gov/pubmed/35115822

Baker, J., Gamer, M., Rauh, J., & Brassen, S. (2022).
Placebo induced expectations of mood enhancement generate a positivity effect in emotional processing. Sci Rep, 12(1), 5345. doi:10.1038/s41598-022-09342-2
https://www.ncbi.nlm.nih.gov/pubmed/35351936

Estudillo-Guerra, M. A., Mesia-Toledo, I., Schneider, J. C., & Morales-Quezada, L. (2021).
The Use of Conditioning Open-Label Placebo in Opioid Dose Reduction: A Case Report and Literature Review. Front Pain Res, 2, 697475. doi:10.3389/fpain.2021.697475
https://www.ncbi.nlm.nih.gov/pubmed/35295534

Feeney, A., Hock, R. S., Fava, M., Hernandez Ortiz, J. M., Iovieno, N., & Papakostas, G. I. (2022).
Antidepressants in children and adolescents with major depressive disorder and the influence of placebo response: A meta-analysis. J Affect Disord, 305, 55-64. doi:10.1016/j.jad.2022.02.074
https://www.ncbi.nlm.nih.gov/pubmed/35247482

Hardman, D. (2022).
Manufacturing the placebo effect. Philosophical Investigations. doi:https://doi.org/10.1111/phin.12341
https://onlinelibrary.wiley.com/doi/abs/10.1111/phin.12341

Heiss, U., Rosenfield, M., & Bernstein, M. H. (2021).
Can the Open Label Placebo Rationale Be Optimized? Front Pain Res, 2, 734882. doi:10.3389/fpain.2021.734882
https://www.ncbi.nlm.nih.gov/pubmed/35295434

Itskovich, E., Bowling, D. L., Garner, J. P., & Parker, K. J. (2022).
Oxytocin and the social facilitation of placebo effects. Mol Psychiatry. doi:10.1038/s41380-022-01515-9
https://www.ncbi.nlm.nih.gov/pubmed/35338314

Koechlin, H., Kharko, A., Probst, T., Pradela, J., Buechi, S., & Locher, C. (2021).
Placebo Responses and Their Clinical Implications in Fibromyalgia: A Meta-Analysis Using SSRI and SNRI Trials. Front Pain Res, 2, 750523. doi:10.3389/fpain.2021.750523
https://www.ncbi.nlm.nih.gov/pubmed/35295427

Mommaerts, J. L. (2022).
Where is the mind in COVID-19 causality? Brain Behav Immun Health, 21, 100434. doi:10.1016/j.bbih.2022.100434
https://www.ncbi.nlm.nih.gov/pubmed/35261991

Perez-Lopez, F. R., & Varikasuvu, S. R. (2022).
Vulvovaginal atrophy management with a laser: the placebo effect or the conditioning Pavlov reflex. Climacteric, 1-4. doi:10.1080/13697137.2022.2050207
https://www.ncbi.nlm.nih.gov/pubmed/35352627

Saunders, G. H., Beukes, E., Uus, K., Armitage, C. J., Kelly, J., & Munro, K. J. (2022).
Shedding Light on SARS-CoV-2, COVID-19, COVID-19 Vaccination, and Auditory Symptoms: Causality or Spurious Conjunction? Front Public Health, 10, 837513. doi:10.3389/fpubh.2022.837513
https://www.ncbi.nlm.nih.gov/pubmed/35296050

Schwartz, M., Fischer, L. M., Blaute, C., Stork, J., Colloca, L., Zollner, C., & Klinger, R. (2021).
Observing treatment outcomes in other patients can elicit augmented placebo effects on pain treatment: a double-blinded randomized clinical trial with patients with chronic low back pain. Pain. doi:10.1097/j.pain.0000000000002513
https://www.ncbi.nlm.nih.gov/pubmed/35262315

Shafir, R., Olson, E., & Colloca, L. (2022).
The neglect of sex: A call to action for including sex as a biological variable in placebo and nocebo research. Contemp Clin Trials, 116, 106734. doi:10.1016/j.cct.2022.106734
https://www.ncbi.nlm.nih.gov/pubmed/35306216

Smith, K. A., Vennik, J., Morrison, L., Hughes, S., Steele, M., Tiwari, R., Bostock, J., Howick, J., Mallen, C., Little, P., Ratnapalan, M., Lyness, E., Misurya, P., Leydon, G. M., Dambha-Miller, H., Everitt, H. A. & Bishop, F. L. (2021).
Harnessing Placebo Effects in Primary Care: Using the Person-Based Approach to Develop an Online Intervention to Enhance Practitioners’ Communication of Clinical Empathy and Realistic Optimism During Consultations. Front Pain Res, 2, 721222. doi:10.3389/fpain.2021.721222
https://www.ncbi.nlm.nih.gov/pubmed/35295512

Sweeney, O., Parepalli, S. A., Mirtorabi, N., Yong Kee, K. L., Feakins, B. G., Aronson, J. K., & Wartolowska, K. A. (2022).
Placebo’s invisible brother: a restricted scoping review of biomedical literature on the nocebo effect. Pain. doi:10.1097/j.pain.0000000000002629
https://www.ncbi.nlm.nih.gov/pubmed/35297813

Tresker, S. (2022).
Consciousness, Placebo Effects, and the Therapeutic Allure of Psychoneuroimmunology. Perspect Biol Med, 65(1), 1-24. doi:10.1353/pbm.2022.0000
https://www.ncbi.nlm.nih.gov/pubmed/35307698

Wampold, B. E. (2021).
Healing in a Social Context: The Importance of Clinician and Patient Relationship. Front Pain Res, 2, 684768. doi:10.3389/fpain.2021.684768
https://www.ncbi.nlm.nih.gov/pubmed/35295467

Wang, R. S., Lembo, A. J., Kaptchuk, T. J., Cheng, V., Nee, J., Iturrino, J., Rao, M., Loscalzo, J., Silvester, J. A. & Hall, K. T. (2021).
Genomic Effects Associated With Response to Placebo Treatment in a Randomized Trial of Irritable Bowel Syndrome. Front Pain Res, 2, 775386. doi:10.3389/fpain.2021.775386
https://www.ncbi.nlm.nih.gov/pubmed/35295415

Weimer, K., Buschhart, C., Broelz, E. K., Enck, P., & Horing, B. (2022).
Bibliometric Properties of Placebo Literature From the JIPS Database: A Descriptive Study. Front Psychiatry, 13, 853953. doi: 10.3389/fpsyt.2022.853953
https://pubmed.ncbi.nlm.nih.gov/35401284/

Wicht, C. A., Mouthon, M., Nsimire Chabwine, J., Gaab, J., & Spierer, L. (2022).
Experience with opioids does not modify the brain network involved in expectations of placebo analgesia. Eur J Neurosci. doi:10.1111/ejn.15645
https://www.ncbi.nlm.nih.gov/pubmed/35266226

Won, J., Bang, H., & Lee, H. (2022).
Effect of Partial vs Full Disclosure of Potential Assignment to Placebo on Participant Blinding, Perceptions of Group Assignment, and Trial Outcomes: A Randomized Clinical Trial. JAMA Netw Open, 5(3), e224050. doi:10.1001/jamanetworkopen.2022.4050
https://www.ncbi.nlm.nih.gov/pubmed/35323953

Zeng, J., Wang, Z., & Yang, X. J. (2022).
Factors predicting clinical and endoscopic remission with placebo therapy in East Asian patients with ulcerative colitis: a systematic review and meta-analysis. Eur J Clin Pharmacol. doi:10.1007/s00228-022-03312-3
https://www.ncbi.nlm.nih.gov/pubmed/35347342

Book Chapters:
Palermo, S. (2022).
Chapter 28 – Neurocognition and placebo analgesia: Linking in functional magnetic resonance imaging. In R. Rajendram, V. B. Patel, V. R. Preedy, & C. R. Martin (Eds.), The Neurobiology, Physiology, and Psychology of Pain (pp. 307-317): Academic Press.
https://doi.org/10.1016/B978-0-12-820589-1.00028-2

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