Placebo Publications April 2022

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Today we present 20 new placebo and nocebo research papers, book chapters, comments and abstracts identified during April 2022. As usual, they are based on new PUBMED publication using the search terms „placebo“ and „nocebo“ and are hand-selected from more than 830 new publications during the preceding month. Previously published monthly updates can be found in our archive. Todays selection as well as all previously identified papers will also go into our placebo research library that currently contains nearly 5,000 relevant papers. If you would like to get access to the full database, please register for our newsletter and provide us with your email address and affiliation.

Ballou, S., Haas, J. W., Iturrino, J., Nee, J., Kirsch, I., Rangan, V., Cheng, V., Lembo, A.. Kaptchuk, T. J. & Kelley, J. M. (2022).
Psychological Predictors of Response to Open-label versus Double-blind Placebo in a Randomized Controlled Trial in Irritable Bowel Syndrome. Psychosom Med. doi:10.1097/PSY.0000000000001078
https://www.ncbi.nlm.nih.gov/pubmed/35412513

Benson, S., Theysohn, N., Kleine-Borgmann, J., Rebernik, L., Icenhour, A., & Elsenbruch, S. (2022).
Positive Treatment Expectations Shape Perceived Medication Efficacy in a Translational Placebo Paradigm for the Gut-Brain Axis. Front Psychiatry, 13, 824468. doi:10.3389/fpsyt.2022.824468
https://www.ncbi.nlm.nih.gov/pubmed/35401247

Boussageon, R., Howick, J., Baron, R., Naudet, F., Falissard, B., Harika-Germaneau, G., Wassouf, I., Gueyffier, F., Jaafari, N. & Blanchard, C. (2022).
How do they add up? The interaction between the placebo and treatment effect: A systematic review. Br J Clin Pharmacol. doi:10.1111/bcp.15345
https://www.ncbi.nlm.nih.gov/pubmed/35384004

Camerone, E. M., Battista, S., Benedetti, F., Carlino, E., Sansone, L. G., Buzzatti, L., Scafoglieri, A. & Testa, M. (2022).
The Temporal Modulation of Nocebo Hyperalgesia in a Model of Sustained Pain. Front Psychiatry, 13, 807138. doi:10.3389/fpsyt.2022.807138
https://www.ncbi.nlm.nih.gov/pubmed/35401252

De Pascalis, V., & Vecchio, A. (2022).
The influence of EEG oscillations, heart rate variability changes, and personality on self-pain and empathy for pain under placebo analgesia. Sci Rep, 12(1), 6041. doi:10.1038/s41598-022-10071-9
https://www.ncbi.nlm.nih.gov/pubmed/35410362

Finan, P. H., Hunt, C. A., Mun, C. J., Lerman, S. F., Tennen, H., Smith, M. T., & Haythornthwaite, J. A. (2022).
The association of affective state with the assimilation of daily pain expectancy and pain experience. Pain. doi:10.1097/j.pain.0000000000002624
https://www.ncbi.nlm.nih.gov/pubmed/35439798

Herring, M. P., Gordon, B. R., Murphy, J., Lyons, M., & Lindheimer, J. B. (2022).
The Interplay Between Expected Psychological Responses to Exercise and Physical Activity in Analogue Generalized Anxiety Disorder: a Cross-sectional Study. Int J Behav Med. doi:10.1007/s12529-022-10081-x
https://www.ncbi.nlm.nih.gov/pubmed/35441339

Hinwood, M., Wall, L., Lang, D., Balogh, Z. J., Smith, A., Dowsey, M., Clarke, P., Choong, P., Bunzli, S. & Paolucci, F. (2022).
Patient and clinician characteristics and preferences for increasing participation in placebo surgery trials: a scoping review of attributes to inform a discrete choice experiment. Trials, 23(1), 296. doi:10.1186/s13063-022-06277-x
https://www.ncbi.nlm.nih.gov/pubmed/35413876

Lunde, S. J., Vuust, P., Garza-Villarreal, E. A., Kirsch, I., Moller, A., & Vase, L. (2022).
Music-Induced Analgesia in Healthy Participants Is Associated With Expected Pain Levels but Not Opioid or Dopamine-Dependent Mechanisms. Front Pain Res, 3, 734999. doi:10.3389/fpain.2022.734999
https://www.ncbi.nlm.nih.gov/pubmed/35445208

Ongaro, G., & Kaptchuk, T. J. (2022).
Reply to Arandia and Di Paolo. Pain, 163(4), e605-e606. doi:10.1097/j.pain.0000000000002489
https://www.ncbi.nlm.nih.gov/pubmed/35302977

Ortega, A., Salazar, J., Galban, N., Rojas, M., Ariza, D., Chavez-Castillo, M., Nava, M., Riano-Garzon, M. E., Diaz-Camargo, E. A., Medina-Ortiz, O. & Bermudez, V. (2022).
Psycho-Neuro-Endocrine-Immunological Basis of the Placebo Effect: Potential Applications beyond Pain Therapy. Int J Mol Sci, 23(8). doi:10.3390/ijms23084196
https://www.ncbi.nlm.nih.gov/pubmed/35457014

O’Sullivan, M., O’Sullivan, E., & Lavelle, A. (2022).
Implications of nocebo in anaesthesia care. Anaesthesia. doi:10.1111/anae.15746
https://www.ncbi.nlm.nih.gov/pubmed/35466400

Rossettini, G., Colombi, A., Carlino, E., Manoni, M., Mirandola, M., Polli, A., Camerone, E. M. & Testa, M. (2022).
Unraveling Negative Expectations and Nocebo-Related Effects in Musculoskeletal Pain. Front Psychol, 13, 789377. doi:10.3389/fpsyg.2022.789377
https://www.ncbi.nlm.nih.gov/pubmed/35369173

Schwartz, M., Stuhlreyer, J., & Klinger, R. (2022).
[Seeing others is believing-analgesic placebo effects through observational learning?]. Schmerz. doi:10.1007/s00482-022-00646-w
https://www.ncbi.nlm.nih.gov/pubmed/35419736

Smith, E. A., Horan, W. P., Demolle, D., Schueler, P., Fu, D. J., Anderson, A. E., Geraci, J., Butlen-Ducuing, F., Link, J., Khin, N. A., Morlock, R. & Alphs, L. D. (2022).
Using Artificial Intelligence-based Methods to Address the Placebo Response in Clinical Trials. Innov Clin Neurosci, 19(1-3), 60-70.
https://www.ncbi.nlm.nih.gov/pubmed/35382067

Tiwari, S. R., Vigotsky, A. D., & Apkarian, A. V. (2022).
On the Relationship Between Pain Variability and Relief in Randomized Clinical Trials. Front Pain Res, 3, 844309. doi:10.3389/fpain.2022.844309
https://www.ncbi.nlm.nih.gov/pubmed/35465296

Weimer, K., Buschhart, C., Broelz, E. K., Enck, P., & Horing, B. (2022).
Bibliometric Properties of Placebo Literature From the JIPS Database: A Descriptive Study. Front Psychiatry, 13, 853953. doi:10.3389/fpsyt.2022.853953
https://www.ncbi.nlm.nih.gov/pubmed/35401284

Wicht, C. A., De Pretto, M., Mouthon, M., & Spierer, L. (2022).
Neural correlates of expectations-induced effects of caffeine intake on executive functions. Cortex, 150, 61-84. doi:10.1016/j.cortex.2022.02.004
https://www.ncbi.nlm.nih.gov/pubmed/35366604

Wolff, B. J., & Wolff, J. E. (2021).
Diarrhea in Placebo Arms of Cancer Studies. Cancer Diagn Progn, 1(5), 379-385. doi:10.21873/cdp.10050
https://www.ncbi.nlm.nih.gov/pubmed/35403170

Yanes, J. A., & Akintola, T. (2022).
Parabrachial Projections to PAG-RVM Axis May Promote Placebo Hypoalgesia and Nocebo Hyperalgesia. J Neurosci, 42(16), 3302-3304. doi:10.1523/JNEUROSCI.2544-21.2022
https://www.ncbi.nlm.nih.gov/pubmed/35444008

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