Today we present 22 new placebo and nocebo research papers, book chapters, comments and abstracts identified during November 2023. As usual, they are based on new PUBMED publication using the search terms „placebo“ and „nocebo“ and are hand-selected from more than 860 new publications during the preceding month. Previously published monthly updates can be found in our archive. Todays selection as well as all previously identified papers will also go into our placebo research library that currently contains nearly 5,000 relevant papers. If you would like to get access to the full database, please register for our newsletter and provide us with your email address and affiliation.
Barnes, K., Nicholls, K., Orlievsky, S., Pei, C., Elder, C., & Faasse, K. (2023).
A novel paradigm examining the remote induction of nocebo effects online. Health Psychol. doi:10.1037/hea0001334
https://www.ncbi.nlm.nih.gov/pubmed/38010778
Bieniek, H., & Babel, P. (2023).
Placebo hypoalgesia induced by operant conditioning: a comparative study on the effects of verbal, token-based, and social rewards and punishers. Sci Rep, 13(1), 20346. doi:10.1038/s41598-023-47482-1
https://www.ncbi.nlm.nih.gov/pubmed/37989856
Campelo, D., Koch, A. J., & Machado, M. (2023).
Caffeine, lactic acid, or nothing: What effect does expectation have on men’s performance and perceived exertion during an upper body muscular endurance task? Int J Health Sci (Qassim), 17(6), 39-42.
https://www.ncbi.nlm.nih.gov/pubmed/37929237
Clemens, K. S., Vang, M., Colloca, L., Sieg, M., Vase, L., Ruble, A., & Geers, A. L. (2023).
The desire for side-effect information in pain treatment: an experimental analysis of contextual and individual difference factors. Pain. doi:10.1097/j.pain.0000000000003025
https://www.ncbi.nlm.nih.gov/pubmed/37975871
Daniali, H., Ruben, M. A., & Flaten, M. A. (2023).
Systematic manipulation of experimenters’ non-verbal behaviors for the investigation of pain reports and placebo effects. Front Psychol, 14, 1248127. doi:10.3389/fpsyg.2023.1248127
https://www.ncbi.nlm.nih.gov/pubmed/38023052
Druart, L., Graham Longsworth, S. E., Terrisse, H., Locher, C., Blease, C., Rolland, C., & Pinsault, N. (2023).
If only they knew! A non-inferiority randomized controlled trial comparing deceptive and open-label placebo in healthy individuals. Eur J Pain. doi:10.1002/ejp.2204
https://www.ncbi.nlm.nih.gov/pubmed/37965922
Evers, A. W. M. (2023).
Open-label placebo hypoalgesia: what works for whom under which circumstances. Pain. doi:10.1097/j.pain.0000000000003109
https://www.ncbi.nlm.nih.gov/pubmed/37963242
Flameling, L. J., Aday, J. S., & van Elk, M. (2023).
Expectancy Effects Cannot Be Neglected in MDMA-Assisted Therapy Research. ACS Chem Neurosci. doi:10.1021/acschemneuro.3c00692
https://www.ncbi.nlm.nih.gov/pubmed/37967550
Hartmann, H., Forkmann, K., Schmidt, K., Kleine-Borgmann, J., Albers, J., Wiech, K., & Bingel, U. (2023).
Open-label placebo treatment does not enhance cognitive abilities in healthy volunteers. Sci Rep, 13(1), 19468. doi:10.1038/s41598-023-45979-3
https://www.ncbi.nlm.nih.gov/pubmed/37945662
Hohenschurz-Schmidt, D., Phalip, J., Chan, J., Gauhe, G., Soliman, N., Vollert, J., Lunde, S. J. & Vase, L. (2023).
Placebo analgesia in physical and psychological interventions: Systematic review and meta-analysis of three-armed trials. Eur J Pain. doi:10.1002/ejp.2205
https://www.ncbi.nlm.nih.gov/pubmed/37985188
Huneke, N. T., Amin, J., Baldwin, D. S., Chamberlain, S. R., Correll, C. U., Garner, M., Hill, C. M., Hou, R., Howes, O. D., Sinclair, J. M., Solmi, M. & Cortese, S. (2023).
Placebo effects in mental health disorders: protocol for an umbrella review. BMJ Open, 13(11), e073946. doi:10.1136/bmjopen-2023-073946
https://www.ncbi.nlm.nih.gov/pubmed/38035741
Li, Y., Du, P., Zhang, X., Ren, C., Shi, X., Dong, X., & Zhang, C. (2023).
Qualified placebo for trials of herbal medicine treatment in rare diseases? A cross-sectional analysis. Orphanet J Rare Dis, 18(1), 373. doi:10.1186/s13023-023-02987-w
https://www.ncbi.nlm.nih.gov/pubmed/38037078
Pipaliya, R. M., Duckett, K. A., Monaghan, N. P., Miller, E. M., Young, G., Brennan, E. A., Nguyen, S. A., Soler, Z. M. & Schlosser, R. J. (2023).
The placebo effect in randomized-controlled trials of medical treatments for chronic rhinosinusitis: A systematic review and meta-analysis. Int Forum Allergy Rhinol. doi:10.1002/alr.23302
https://www.ncbi.nlm.nih.gov/pubmed/37985206
Richardson, M., Cathro, M., & Kleinstauber, M. (2023).
Nocebo Hypothesis Cognitive Behavioural Therapy (NH-CBT) for non-epileptic seizures: a consecutive case series. Behav Cogn Psychother, 1-20. doi:10.1017/S1352465823000565
https://www.ncbi.nlm.nih.gov/pubmed/38018147
Sacca, V., Wen, Y., Hodges, S., & Kong, J. (2023).
Modulation effects of repeated transcranial direct current stimulation on the dorsal attention and frontal parietal networks and its association with placebo and nocebo effects. Neuroimage, 284, 120433. doi:10.1016/j.neuroimage.2023.120433
https://www.ncbi.nlm.nih.gov/pubmed/37939891
Tang, B., Livesey, E., & Colagiuri, B. (2023).
Choice over placebo administration enhances open-label placebo hypoalgesia. Pain. doi:10.1097/j.pain.0000000000003108
https://www.ncbi.nlm.nih.gov/pubmed/37963238
Totsch, S. K., & Sorge, R. E. (2023).
A novel investigation of placebo analgesia through social communication in mice. Behav Brain Res, 459, 114773. doi:10.1016/j.bbr.2023.114773
https://www.ncbi.nlm.nih.gov/pubmed/38000532
Tseng, P. T., Zeng, B. S., Hsu, C. W., Thompson, T., Stubbs, B., Hsueh, P. R., Su, K. P., Chen, Y. W., Chen, T. Y., Wu, Y. C., Lin, P. Y., Carvalho, A. F., Li, D. J., Yeh, T. C., Sun, C. K., Cheng, Y. S., Shiue, Y. L., Liang, C. S. & Tu, Y. K. (2023).
The difference in all-cause mortality between COVID-19 patients treated with standard of care plus placebo and those treated with standard of care alone: a network meta-analysis of randomised controlled trials of immunomodulatory kinase inhibitors. J R Soc Med, 1410768231202657. doi:10.1177/01410768231202657
https://www.ncbi.nlm.nih.gov/pubmed/37971412
Yang, J., Guo, J., Yang, X., Chen, J., Bai, T., & Liu, S. (2023).
Nocebo effects and influencing factors in the randomized clinical trials of chronic constipation: A systematic review and meta-analysis. Neurogastroenterol Motil, e14708. doi:10.1111/nmo.14708
https://www.ncbi.nlm.nih.gov/pubmed/37936549
Yavropoulou, M. P., Kasdagli, M. I., Makras, P., Diomatari, K. M., Anastasilakis, A. D., Mitsikostas, D. D., Kassi, E., Sfikakis, P. P. & Kravvariti, E. (2023).
Nocebo-associated treatment discontinuation with subcutaneous anti-osteoporotic drugs. A systematic review and meta-analysis of placebo-arm dropouts in randomized-controlled trials. Maturitas, 179, 107874. doi:10.1016/j.maturitas.2023.107874
https://www.ncbi.nlm.nih.gov/pubmed/37976923
Zagatto, A. M., Lopes, V. H. F., Dutra, Y. M., de Poli, R. A. B., Dolan, E., Rasica, L., Murias, J. M. & de Azevedo, P. (2023).
Sodium bicarbonate induces alkalosis, but improves high-intensity cycling performance only when participants expect a beneficial effect: a placebo and nocebo study. Eur J Appl Physiol. doi:10.1007/s00421-023-05368-0
https://www.ncbi.nlm.nih.gov/pubmed/38032386
Zeglen, M., Kryst, L., & Babel, P. (2023).
Diet, gym, supplements, or maybe it is all in your mind? A systematic review and meta-analysis of studies on placebo and nocebo effects in weight loss in adults. Obes Rev. doi:10.1111/obr.13660 https://www.ncbi.nlm.nih.gov/pubmed/37950372
Placebo in the media
LETTER On placebos – Newsletter124 – Health Sense
By Colin Brewer
https://www.healthsense-uk.org/publications/newsletter/newsletter-124/370-124-brewer.html
Download PDF of Newsletter here.