Today we present 16 new placebo and nocebo research papers, book chapters, comments and abstracts identified during December 2023. As usual, they are based on new PUBMED publication using the search terms „placebo“ and „nocebo“ and are hand-selected from more than 819 new publications during the preceding month. Previously published monthly updates can be found in our archive. Todays selection as well as all previously identified papers will also go into our placebo research library that currently contains around 5,400 relevant papers. If you would like to get access to the full database, please register for our newsletter and provide us with your email address and affiliation.
Babel, P. (2023).
Rethinking placebo: Exploring the effectiveness of open-label placebos. Eur J Pain. doi:10.1002/ejp.2226
https://www.ncbi.nlm.nih.gov/pubmed/38102843
Basedau, H., Ornello, R., Matteis, E., Davaasuren, B., Kadyrova, B., Vuralli, D., Bozhenko, M., Azizova, I., Bitsadze, N., Eralieva, E., Ashina, M., Mitsikostas, D. & Puledda, F. (2023).
Placebo and nocebo in the treatment of migraine: How much does real world effectiveness depend on contextual effects? Cephalalgia, 43(12), 3331024231218392. doi:10.1177/03331024231218392
https://www.ncbi.nlm.nih.gov/pubmed/38041833
Cormack, B., & Rossettini, G. (2023).
Are patients picking up what we are putting down? Considering nocebo effects in exercise for musculoskeletal pain. Front Psychol, 14, 1291770. doi:10.3389/fpsyg.2023.1291770
https://www.ncbi.nlm.nih.gov/pubmed/38078230
de Graaf, M. C. G., Lawton, C. L., Croden, F., Smolinska, A., Winkens, B., Hesselink, M. A. M., van Rooy, G., Weegels, P. L., Shewry, P. R., Houghton, L. A., Witteman, B. J. M., Keszthelyi, D., Brouns, F., Dye, L. & Jonkers, D. (2024).
The effect of expectancy versus actual gluten intake on gastrointestinal and extra-intestinal symptoms in non-coeliac gluten sensitivity: a randomised, double-blind, placebo-controlled, international, multicentre study. Lancet Gastroenterol Hepatol, 9(2), 110-123. doi:10.1016/S2468-1253(23)00317-5
https://www.ncbi.nlm.nih.gov/pubmed/38040019
Friehs, T., Milde, C., Glombiewski, J. A., & Kube, T. (2023).
Change in pain expectations but no open-label placebo analgesia: An experimental study using the heat pain paradigm. Eur J Pain. doi:10.1002/ejp.2216
https://www.ncbi.nlm.nih.gov/pubmed/38108636
Geers, A. L., Spotts, E. K., Vang, M., Mayer, S. R., & Miller, F. G. (2023).
The Use of Authorized Concealment to Minimize Nocebo Side Effects: A Survey of US Public Attitudes. Psychother Psychosom, 92(6), 391-398. doi:10.1159/000535011
https://www.ncbi.nlm.nih.gov/pubmed/38043522
Gomeni, R., Hopkins, S., Bressolle-Gomeni, F., & Fava, M. (2023).
Interpreting clinical trial outcomes complicated by placebo response with an assessment of false-negative and true-negative clinical trials in depression using propensity-weighting. Transl Psychiatry, 13(1), 388. doi:10.1038/s41398-023-02685-y
https://www.ncbi.nlm.nih.gov/pubmed/38097546
Montag, L. T., Bisson, E. J., Duggan, S., Gregory, T., Murphy, G., Gilron, I., Wilson, R. & Salomons, T. V. (2023).
Patient Expectations and Therapeutic Alliance Affect Pain Reduction Following Lidocaine Infusion in an Interdisciplinary Chronic Pain Clinic. J Pain. doi:10.1016/j.jpain.2023.11.026
https://www.ncbi.nlm.nih.gov/pubmed/38056545
Rooney, T., Sharpe, L., Todd, J., Richmond, B., & Colagiuri, B. (2023).
The relationship between expectancy, anxiety, and the nocebo effect: a systematic review and meta-analysis with recommendations for future research. Health Psychol Rev, 17(4), 550-577. doi:10.1080/17437199.2022.2125894
https://www.ncbi.nlm.nih.gov/pubmed/36111435
Rubanets, D., Badzinska, J., Klosowska, J., Babel, P., & Bajcar, E. A. (2023).
Pain Rating is Worth a Thousand Words: Nocebo Hyperalgesia Induced by Verbal Modeling Prevails Over the Effects of Symbolic Modeling and Verbal Suggestion. J Pain. doi:10.1016/j.jpain.2023.11.025
https://www.ncbi.nlm.nih.gov/pubmed/38056544
Saueressig, T., Owen, P. J., Pedder, H., Tagliaferri, S., Kaczorowski, S., Altrichter, A., Richard, A., Miller, C. T., Donath, L. & Belavy, D. L. (2023).
The importance of context (placebo effects) in conservative interventions for musculoskeletal pain: A systematic review and meta-analysis of randomized controlled trials. Eur J Pain. doi:10.1002/ejp.2222
https://www.ncbi.nlm.nih.gov/pubmed/38116995
Strickland, J. C., Gelino, B. W., Naude, G. P., Harbaugh, J. C., Schlitzer, R. D., Mercincavage, M., Strasser, A. A. & Johnson, M. W. (2024).
Effect of nicotine expectancy and nicotine dose reduction on cigarette demand, withdrawal alleviation, and puff topography. Drug Alcohol Depend, 254, 111042. doi:10.1016/j.drugalcdep.2023.111042
https://www.ncbi.nlm.nih.gov/pubmed/38086213
Tani, H. (2023).
Can placebo effect save your life? Psychiatry Clin Neurosci, 77(12), 629. doi:10.1111/pcn.13600
https://www.ncbi.nlm.nih.gov/pubmed/38062575
Taniguchi, A. N., Sutton, S. R., Mills, J. F., Nguyen, S. A., Rizk, H. G., Meyer, T. A., Nguyen, J. P. & Lambert, P. R. (2023).
Placebo effect in randomized controlled trials for Meniere’s disease: A meta-analysis. Am J Otolaryngol, 45(2), 104178. doi:10.1016/j.amjoto.2023.104178
https://www.ncbi.nlm.nih.gov/pubmed/38101129
Wittayer, M., Sandikci, V., Ebert, A., Koehler, C., Szabo, K., & Hoyer, C. (2023).
[Potential Impact of Public Communication on Emergency Presentations due to Headache during the Covid-19 Pandemic]. Gesundheitswesen. doi:10.1055/a-2146-6286
https://www.ncbi.nlm.nih.gov/pubmed/38065548
Zeglen, M., Kryst, L., & Babel, P. (2024).
Want to be fit? Start with your mind! The role of the placebo effect in physical fitness in children: a preliminary systematic review and meta-analysis. Int J Obes, 48(2), 177-187. doi:10.1038/s41366-023-01413-2
https://www.ncbi.nlm.nih.gov/pubmed/38081926
Download PDF here.